Anti-Hu CD334 Purified FGFR4 Monoclonal Antibody

Product Name

Anti-Hu CD334 Purified FGFR4 Monoclonal Antibody

View all FGFR4 Antibodies

SKU/Catalog Number

M00769-1

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Hu CD334 Purified FGFR4 Monoclonal Antibody (Catalog# M00769-1). Tested in Flow Cytometry, ICC application(s). This antibody reacts with Human.

Storage & Handling

Store at 2-8°C. Do not freeze.

Cite This Product

Anti-Hu CD334 Purified FGFR4 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00769-1)

Host

Mouse

Contents

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Clonality

Monoclonal

Clone Number

4FR6D3

Isotype

Mouse IgG1 kappa

Immunogen

NIH 3T3 cells transfected with full length human CD334. The mouse monoclonal antibody 4FR6D3 reacts with an extracellular epitope of CD334, the fibroblast growth factor receptor 4, which is an approximately 88 kDa receptor tyrosine kinase expressed in variety of tissues.

Reactive Species

M00769-1 is reactive to FGFR4 in Human

Observed Molecular Weight

42 kDa

Calculated molecular weight

88.0 kDa

Background of FGFR4

CD334 / FGFR4 (fibroblast growth factor receptor 4), a transmembrane tyrosine kinase, which is expressed in many tissues, such as in lung, kidney, muscle, heart, pancreas, intestine and other, acts as a receptor for several fibroblast growth factors, namely FGF1, FGF2, FGF6, FGF8, and FGF19. Interaction with these growth factors initiates in cell the signaling cascades leading to the mitogenesis and cell differentiation. Presence of CD334 Gly338Arg allele correlates with prognostic parameters in various cancer studies. CD334 plays multiple roles in the organism, including those of muscle regeneration, cholesterol-to-bile acid metabolism, or glucose homeostasis.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

M00769-1 is guaranteed for Flow Cytometry, ICC Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Flow cytometry: 2-6 μg/ml.

Validation Images & Assay Conditions

See full target information FGFR4

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