Product Info Summary
SKU: | A00587Y773 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IHC |
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Product info
Product Name
Anti-Integrin Beta 3 (phospho-Y773) ITGB3 Antibody
View all Integrin beta 3/CD61 Antibodies
SKU/Catalog Number
A00587Y773
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Integrin Beta 3 (phospho-Y773) ITGB3 Antibody catalog # A00587Y773. Tested in IHC applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Integrin Beta 3 (phospho-Y773) ITGB3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00587Y773)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthetic peptide, corresponding to amino acids 300-350 of Human ULK1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A00587Y773 is reactive to ITGB3 in Human, Mouse, Rat
Applications
A00587Y773 is guaranteed for IHC Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
87.058kDa
Background of Integrin beta 3/CD61
Transcriptional regulator that binds to DNA as a dimer or as a tetramer, but not as a monomer. Binds to G-doublets in an A/T-rich environment; the preferred motif is a tandem repeat of 5'-. ATTGGTTA-3' combined with a 5'-TTATTA-3' box. Binds to nucleosomes By similarity. Binds to chromatin and interacts selectively with histone H3 that is not methylated at 'Lys-4', not phosphorylated at 'Thr-3' and not methylated at 'Arg-2'. Functions as a sensor of histone H3 modifications that are important for the epigenetic regulation of gene expression. Functions as a transcriptional activator and promotes the expression of otherwise tissue-specific self-antigens in the thymus, which is important for self tolerance and the avoidance of autoimmune reactions.
Nagamine K., Nat. Genet. 17:393-398(1997).
Aaltonen J., Nat. Genet. 17:399-403(1997).
Hattori M., Nature 405:311-319(2000).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
IHC: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Immunohistochemistry (IHC) analyzes of p-Integrin β3 (Y773) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.
Protein Target Info & Infographic
Gene/Protein Information For ITGB3 (Source: Uniprot.org, NCBI)
Gene Name
ITGB3
Full Name
Integrin beta-3
Weight
87.058kDa
Superfamily
integrin beta chain family
Alternative Names
CD61 antigen; CD61; GP3A; GP3Aplatelet glycoprotein IIIa; GPIIIA; GPIIIaintegrin beta-3; INGRB3; Integrin beta 3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); ITG B3; ITGB3; Platelet membrane glycoprotein IIIa ITGB3 BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, GT integrin subunit beta 3 integrin beta-3|antigen CD61|integrin beta 3|integrin beta chain, beta 3|integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)|platelet membrane glycoprotein IIIa
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on ITGB3, check out the ITGB3 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for ITGB3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Integrin Beta 3 (phospho-Y773) ITGB3 Antibody (A00587Y773)
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No publications found for A00587Y773
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