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Product Info Summary
| SKU: | M00217-5 |
|---|---|
| Size: | 100 μl/vial |
| Reactive Species: | Human, Monkey, Mouse, Rat |
| Host: | Rabbit |
| Application: | IP, IHC, WB |
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Product info
Product Name
Anti-LKB1/STK11 Antibody (Monoclonal, 34S49)
SKU/Catalog Number
M00217-5
Size
100 μl/vial
Form
Liquid
Description
Boster Bio Anti-LKB1/STK11 Antibody (Monoclonal, 34S49) catalog # M00217-5. Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse, Rat, Monkey.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-LKB1/STK11 Antibody (Monoclonal, 34S49) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00217-5)
Host
Rabbit
Contents
Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.
Clonality
Monoclonal
Clone Number
34S49
Immunogen
Recombinant protein within human LKB1 aa 3-398.
Reactive Species
M00217-5 is reactive to STK11 in Human, Monkey, Mouse, Rat
Calculated molecular weight
48.6 kDa
Background of STK11
Serine/threonine kinase 11 or LKB1 is a protein kinase which in humans is encoded by the STK11 gene. The STK11 gene, which encodes a member of the serine/threonine kinase, regulates cell polarity and functions as a tumour suppressor. STK11 is a primary upstream kinase of adenine monophosphate-activated protein kinase (AMPK), a necessary element in cell metabolism that is required for maintaining energy homeostasis. It has been found that LKB1 physically associates with p53 and regulates specific p53-dependent apoptosis pathways. The STK11 gene extends over 23 kb of genomic DNA and is composed of 9 exons, which are transcribed in telomere-to-centromere direction.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M00217-5 is guaranteed for IP, IHC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blot, 1:500-2000
Immunohistochemistry, 1:50-200
ImmunoPrecipitation, 1:50
Validation Images & Assay Conditions
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Specific Publications For Anti-LKB1/STK11 Antibody (Monoclonal, 34S49) (M00217-5)
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