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MRC1 antibody (A02285-2) performs well in ELISA, IF, IHC, WB and shows reactivity with Human, Monkey, Mouse, Rat.

Validated for inter-lot consistency, specificity, and reproducibility
Committed to quality since 1993
Over 65 Publications

a02285 2 mrc1 primary antibodies if testing 6

IF analysis of MRC1 using anti-MRC1 antibody (A02285-2).
MRC1 was detected in a paraffin-embedded section of human tonsil tissue. Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 5 μg/mL rabbit anti-MRC1 Antibody (A02285-2) overnight at 4°C. DyLight®550 Conjugated Goat Anti-Rabbit IgG (BA1135) was used as secondary antibody at 1:500 dilution and incubated for 30 minutes at 37°C. The section was counterstained with DAPI. Visualize using a fluorescence microscope and filter sets appropriate for the label used.

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Anti-Mannose Receptor/MRC1 Picoband® Antibody

Name: Anti-Mannose Receptor/MRC1 Picoband® Antibody
Brand: Boster Bio
SKU: A02285-2
Price: 370 USD
Availability: InStock
Rating: 100 (1 reviews)

MRC1 antibody

65 Publications|

1 Review

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Reactive Species	Host	Application
Human, Monkey, Mouse, Rat	Rabbit	ELISA, IF, IHC, WB

Tested Applications

MRC1 antibody was positively detected by WB in:

rat lung tissue, mouse lung tissue, human liver tissue, monkey lung tissue

Suggested blocking solution with 5% non-fat milk or BSA; (*)Recommended protein loading: 20-40 ug per lane

MRC1 antibody was positively detected by IHC in:

human liver cancer tissue, human tonsil tissue, mouse liver tissue, rat liver tissue

Use TE buffer pH 9.0 for antigen retrieval; (*) citrate buffer pH 6.0 is an alternative.

MRC1 antibody was positively detected by IF in:

human tonsil tissue, mouse liver tissue

Reactive Data

Boster Guarantee: All Tested Recommend Predicted species What is this?

IHC

ELISA

Rat

Tested

Recommend

Mouse

Tested

Recommend

Human

Tested

Recommend

Monkey

Tested

Recommend

Rabbit

Predicted

Product Information

Product Name

Anti-Mannose Receptor/MRC1 Picoband® Antibody
View all MRC1 Antibodies

Form

Lyophilized

Uniprot

P22897

Gene ID

4360

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Host

Rabbit

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human Mannose Receptor/MRC1 recombinant protein (Position: D21-A1140).

Cross-Reactivity

No cross-reactivity with other proteins.

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Observed Molecular Weight

190-200 kDa

Calculated Molecular Weight

166.0 kDa

Background of MRC1

The mannose receptor (Cluster of Differentiation 206, CD206) is a C-type lectin primarily present on the surface of macrophages, immature dendritic cells and liver sinusoidal endothelial cells, but is also expressed on the surface of skin cells such as human dermal fibroblasts and keratinocytes. It is mapped to 10p12.33. The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.

Cite This Product

Anti-Mannose Receptor/MRC1 Picoband® Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02285-2)

Protocols

Western Blot protocol for MRC1 antibody

Review Protocol

Immunohistochemistry (IHC) protocol for MRC1 antibody

Review Protocol

Immunofluorescence (IF) protocol for MRC1 antibody

Review Protocol

Publications

Macrophages orchestrate tail regeneration in lizards Scincella tsinlingensis through spatiotemporal control of immunity, oxidative stress, and myogenesis

Published: 2026-08-06

Journal: Frontiers in Cell and Developmental Biology

Application: IHC

Impact Factor: 5.30

Species: Lizards

PMID: 42625655

SKU	A02285-2
Application	Immunohistochemistry (paraffin-embedded)
Blocking step	5% BSA as a blocking agent for 30 min at 37°C
Sample	Mouse skin
Fixative	Fixed with 4% paraformaldehyde
Primary Ab Incubation	37°C for 30 minutes
Primary Ab Incubation diluent	5% BSA in TBS
Primary Ab Concentration	1ug/ml
Secondary Antibody	SABC kit from Boster Bio, (SA1022)
Secondary Ab Dilution	The kit was ready to use, no dilution needed
Secondary Ab Incubation	at 37°C for 30 min

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Anti-Mannose Receptor/MRC1 Picoband® Antibody

MRC1 antibody

Overview

Tested Applications

Recommend Dilution

Reactive Data

Product Information

Protocols

Publications

Macrophages orchestrate tail regeneration in lizards Scincella tsinlingensis through spatiotemporal control of immunity, oxidative stress, and myogenesis

Intranasal delivery of curcumin via biomimetic microglial membrane-coated chitosan nanoparticles alleviates depressive-like behaviors in LPS models

Comparative Analysis of Extracellular Vesicle‐Like Particles From Different Processing Gastrodia elata Bl.: Physicochemical Properties, Biosafety, and Neuroprotection Potential as a Functional Food Ingredient

Astragaloside lV-Loaded Mesoporous Silica Nanoparticles Attenuated Cerebral Ischemic Injury via Iron Overload and Neuroinflammation

Neuregulin 4 improves white adipose tissue inflammation in mice with polycystic ovary syndrome

Pulmonary microbiota-associated formononetin modulates microglial activation in asthma-related anxiety

Formononetin attenuates cerebral ischemia-reperfusion injury by regulating microglial glycolysis through AMPK

Fraxin Attenuates Rheumatoid Arthritis by Regulating Macrophage Polarization and Inhibiting Fibroblast-like Synoviocyte Proliferation

An injectable multi-functional strontium based gentiopicroside hydrogel accelerates bone regeneration via immunomodulation and promoting osteo-/angiogenesis effects

Immunomodulatory mesoporous bioactive glass/interleukin-4 nanocomplex promotes bone regeneration

Photobiomodulation mitigates chondrocyte catabolism in osteoarthritis by modulating macrophage M1 polarization through the IL-6/JAK/STAT pathway

Identification and Validation of β-Carotene-Interacting Drivers in Diet-Induced Obesity Using Bioinformatics and Experimental Approaches

Size Effect of Mesoporous Bioactive Glass on Macrophage Polarization

Omentin-1 reduced synovial M1 macrophages through SIRT6 signaling pathway and alleviated knee osteoarthritis response in mice

Hydrogen bonding enforced supramolecular multifunctional nanocoating for implant osseointegration

pH-responsive hydrogel system loaded with curcumin-preconditioned mesenchymal stem cell exosomes for enhanced diabetic wound healing in orthopedic applications

Targeting macrophage-myofibroblast transition with Caulis spatholobi to attenuate renal interstitial fibrosis: integrated UHPLC-Q-Exactive Orbitrap-MS, network pharmacology, and experimental validation

Penicillamine-based chiral ZnO nanoparticles: A dual mechanism for infected wound healing via antibacterial activity and immune regulation

ROS-responsive nanoassembly co-delivering chlorogenic acid and copper accelerates healing of infected burns via oxidative stress mitigation and macrophage M2 polarization

A multifunctional biomimetic nanoplatform combined with immune checkpoint blockade for triple-negative breast cancer immunotherapy through inhibiting polarization of M2 macrophages

Construction of ROS-responsive cascade-targeted liposomes and investigation of their anti-AD effects

Effect of the TIM-3/Gal-9 signaling pathway on macrophage polarization in peri-implantitis

Human adipose-derived mesenchymal stem cell-derived exosomes induce epithelial remodeling and anti-scar healing revealed by single-cell RNA sequencing

Aqueous extract of Saposhnikovia divaricata root alleviates rheumatoid arthritis by acting on TNF-α and RAGE signaling pathways

In Situ Programming of the Tumor Microenvironment to Alleviate Immunosuppression for Pancreatic Cancer Immunotherapy

Poliumoside alleviates microglia-mediated inflammation and blood-brain barrier disruption via modulating the polarization of microglia after ischemic stroke in mice

Application of sodium alginate and polyethylene glycol bilayer multifunctional hydrogel microneedles in infectious and diabetic wounds

Alleviation of Microglia Mediating Hippocampal Neuron Impairments and Depression-Related Behaviors by Urolithin B via the SIRT1-FOXO1 Pathway

Modulation of Macrophage Polarization in Rheumatoid Arthritis Therapy via Targeted Delivery of Bulleyaconitine A

L-arginine modified mesoporous bioactive glass with ROS scavenging and NO release for periodontitis treatment

Sustained-Release H2S Nanospheres Regulate the Inflammatory Microenvironment of Wounds, Promote Angiogenesis and Collagen Deposition, and Accelerate Diabetic Wound Healing

Yunvjian decoction attenuates lipopolysaccharide-induced acute lung injury by inhibiting NF-κB/NLRP3 pathway and pyroptosis

Nasal mucosal mesenchymal stem cells promote repair of sciatic nerve injury in rats by modulating the inflammatory microenvironment

Immunomodulatory and osteogenic effects of chitosan-based injectable hydrogel with geniposide-loaded mesoporous bioactive glass

Jinwu Jiangu capsule attenuates rheumatoid arthritis via the SLC7A11/GSH/GPX4 pathway in M1 macrophages

A microenvironment-modulating dressing with proliferative degradants for the healing of diabetic wounds

Deleting fibroblast growth factor 2 in macrophages aggravates septic acute lung injury by increasing M1 polarization and inflammatory cytokine secretion

Immunomodulatory hydrogel patches loaded with curcumin and tannic acid assembled nanoparticles for radioactive dermatitis repair and radioprotection

Fat mass and obesity–mediated m6A modification modulates neuroinflammatory responses after traumatic brain injury

“Butterfly-effect” nano-platforms for cascade immune amplification and tumor clearance through multi-modal therapy and immune sensitization

Dynamic processes of positive/negative immune-vascular crosstalk loop via functional MRI-guided monitor

Baicalin nanodelivery system based on functionalized metal-organic framework for targeted therapy of osteoarthritis by modulating macrophage polarization

M2 Macrophage-Derived Extracellular Vesicles Encapsulated in Hyaluronic Acid Alleviate Osteoarthritis by Modulating Macrophage Polarization

Combining decellularized adipose tissue with decellularized adventitia extravascular matrix or small intestinal submucosa matrix for the construction of vascularized tissue-engineered adipose

Effect and mechanism of chlorogenic acid on cognitive dysfunction in mice by lipopolysaccharide-induced neuroinflammation

Application of omics technology to investigate the mechanism underlying the role of San Hua Tang in regulating microglia polarization and blood-brain barrier protection following ischemic stroke

Hydrophilic surface-modified 3D printed flexible scaffolds with high ceramic particle concentrations for immunopolarization-regulation and bone regeneration

Reversing inflammatory microenvironment by a single intra-articular injection of multi-stimulus responsive lipogel to relieve rheumatoid arthritis and promote joint repair

Epigallocatechin-3-gallate (EGCG) based metal-polyphenol nanoformulations alleviates chondrocytes inflammation by modulating synovial macrophages polarization

Controlled intracellular aggregation of magnetic particles improves permeation and retention for magnetic hyperthermia promotion and immune activation

Non–small cell lung cancer-derived exosomes promote proliferation, phagocytosis, and secretion of microglia via exosomal microRNA in the metastatic microenvironment

Human adipose-derived mesenchymal stem cells-derived exosomes encapsulated in pluronic F127 hydrogel promote wound healing and regeneration

Triptolide attenuates LPS-induced activation of RAW 264.7 macrophages by inducing M1-to-M2 repolarization via the mTOR/STAT3 signaling

Pore Size of 3D-Printed Polycaprolactone/Polyethylene Glycol/Hydroxyapatite Scaffolds Affects Bone Regeneration by Modulating Macrophage Polarization and the Foreign Body Response

Exosomes Derived From M2 Microglia Cells Attenuates Neuronal Impairment and Mitochondrial Dysfunction in Alzheimer’s Disease Through the PINK1/Parkin Pathway

Mitochondrial targeted melanin@mSiO2 yolk-shell nanostructures for NIR-Ⅱ-driven photo-thermal-dynamic/immunotherapy

IL-1β pre-stimulation enhances the therapeutic effects of endometrial regenerative cells on experimental colitis

Protective Effects of Two Safflower Derived Compounds, Kaempferol and Hydroxysafflor Yellow A, on Hyperglycaemic Stress-Induced Podocyte Apoptosis via Modulating of Macrophage M1/M2 Polarization

Protective Effects of Thalidomide on High-Glucose-Induced Podocyte Injury through In Vitro Modulation of Macrophage M1/M2 Differentiation

Near infrared light-triggered on-demand Cur release from Gel-PDA@Cur composite hydrogel for antibacterial wound healing

Autologous bionic tissue for inguinal hernia repair

Network pharmacology identification of mechanisms of cerebral ischemia injury amelioration by Baicalin and Geniposide

Copper-nanoparticle-embedded hydrogel for killing bacteria and promoting wound healing with photothermal therapy

Expression of Programmed Death-Ligand 1 in Laryngeal Carcinoma and its Effects on Immune Cell Subgroup Infiltration

Increased Macrophage Activation Inhibited by Tacrolimus in the Kidney of Diabetic Rats

Review

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