Anti-MUC1 Antibody Picoband™

MUC1 antibody

Boster Bio Anti-MUC1 Antibody Picoband™ catalog # PB9145. Tested in IHC applications. This antibody reacts with Human. Cited in 10 publication(s).

Product Info Summary

SKU: PB9145
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: IHC

Customers Who Bought This Also Bought

Product Name

Anti-MUC1 Antibody Picoband™

View all MUC1 Antibodies

SKU/Catalog Number

PB9145

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-MUC1 Antibody Picoband™ catalog # PB9145. Tested in IHC applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-MUC1 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9145)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human MUC1 recombinant protein (Position: R945-G1097). Human MUC1 shares 56% amino acid (aa) sequence identity with mouse MUC1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PB9145 is reactive to MUC1 in Human

Applications

PB9145 is guaranteed for IHC Boster Guarantee

Observed Molecular Weight

47 kDa

Calculated molecular weight

122.102kDa

Background of MUC1

Mucin 1, cell surface associated (MUC1) or polymorphic epithelial mucin (PEM) is a mucin encoded by the MUC1 gene in humans. This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. It is mapped to 1q22. Mucin 1 is a transmembrane mucin normally expressed on the apical borders of secretory epithelial cells. Overexpression of Mucin 1 is often associated with colon, breast, ovarian, lung and pancreatic cancers. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Mucin 1 stimulated ESR1-mediated transcription and contributed to estradiol-mediated growth and survival of breast cancer cells. This gene also can suppress pulmonary innate immunity, and its antiinflammatory activity may play an important modulatory role during microbial infection.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

View more details

Innovating Scientists Reward

If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists worldwide.

Submit A Review

Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat

Validation Images & Assay Conditions

Gene/Protein Information For MUC1 (Source: Uniprot.org, NCBI)

Gene Name

MUC1

Full Name

Mucin-1

Weight

122.102kDa

Alternative Names

Breast carcinoma-associated antigen DF3; Carcinoma-associated mucin; CD227 antigen; CD227; DF3 antigen; EMA; Episialin; H23 antigen; H23AG; KL-6; MAM6; MUC-1; MUC1/ZD; mucin 1, cell surface associated; mucin 1, transmembrane; Mucin-1; Peanut-reactive urinary mucin; PEM; PEMMUC-1/SEC; PEMT; Polymorphic epithelial mucin; PUMMUC-1/X; tumor associated epithelial mucin; Tumor-associated epithelial membrane antigen; Tumor-associated mucin MUC1 ADMCKD, ADMCKD1, ADTKD2, CA 15-3, CD227, EMA, H23AG, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X/ZD, PEM, PEMT, PUM, MUC1 mucin 1, cell surface associated mucin-1|H23 antigen|breast carcinoma-associated antigen DF3|cancer antigen 15-3|carcinoma-associated mucin|episialin|krebs von den Lungen-6|mucin 1, transmembrane|peanut-reactive urinary mucin|polymorphic epithelial mucin|tumor associated epithelial mucin|tumor-associated epithelial membrane antigen

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on MUC1, check out the MUC1 Infographic

MUC1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for MUC1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

PB9145 has been cited in 10 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Combination of fasudil and celecoxib promotes the recovery of injured spinal cord in rats better than celecoxib or fasudil alone

Puerarin protects brain tissue against cerebral ischemia/reperfusion injury by inhibiting the inflammatory response

Effect of cyclooxygenase-2 inhibition on the development of post-traumatic stress disorder in rats

MicroRNA-101 regulates the viability and invasion of cervical cancer cells

Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) Downregulates the Expression of Protumor Factors Cyclooxygenase-2 and Inducible Nitric Oxide Synthase in a GM-CSF Receptor-Independent Manner in Cervical Cancer Cells

Odontogenic epithelial proliferation is correlated with COX-2 expression in dentigerous cyst and ameloblastoma

Anti-inflammatory Effects of Phyllanthus emblica L on Benzopyrene-Induced Precancerous Lung Lesion by Regulating the IL-1?/miR-101/Lin28B Signaling Pathway

miR-144 and targets, c-fos and cyclooxygenase-2 (COX2), modulate synthesis of PGE2 in the amnion during pregnancy and labor

Glycyrrhizic Acid Attenuates Sepsis-Induced Acute Kidney Injury by Inhibiting NF-?B Signaling Pathway

MicroRNA-27b Regulates Mitochondria Biogenesis in Myocytes

Have you used Anti-MUC1 Antibody Picoband™?

Submit a review and receive an Amazon gift card.

  • $25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
  • $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit A Review

Be the first to review Anti-MUC1 Antibody Picoband™

*The first user to submit a review for a product is eligible for Boster's Innovating Scientists Reward, which gives product credits. This is in addition to the gift card reward.

Have a question?

Find answers in Q&As, reviews.

Can't find your answer?

Submit your question

4 Customer Q&As for Anti-MUC1 Antibody Picoband™

Question

My colleagues were content with the WB result of your anti-MUC1 antibody. However we have seen positive staining in mammary carcinoma isoform 9: secreted. using this antibody. Is that expected? Could you tell me where is MUC1 supposed to be expressed?

Verified Customer

Verified customer

Asked: 2020-04-21

Answer

From literature, mammary carcinoma does express MUC1. Generally MUC1 expresses in apical cell membrane, isoform 5: secreted., isoform y: secreted., isoform 9: secreted., mucin-1 subunit beta: cell membrane. Regarding which tissues have MUC1 expression, here are a few articles citing expression in various tissues:
Cervix carcinoma, Pubmed ID: 15969018
Cervix carcinoma, and Erythroleukemia, Pubmed ID: 23186163
Lung, Pubmed ID: 8604237
Mammary carcinoma, Pubmed ID: 1697589, 11341784
Pancreatic carcinoma, Pubmed ID: 2394722

Boster Scientific Support

Answered: 2020-04-21

Question

We have seen staining in human carcinoma. Do you have any suggestions? Is anti-MUC1 antibody supposed to stain carcinoma positively?

Verified Customer

Verified customer

Asked: 2020-02-10

Answer

From literature carcinoma does express MUC1. From Uniprot.org, MUC1 is expressed in body of stomach, pancreatic carcinoma, mammary carcinoma, carcinoma, cervix carcinoma, thyroid, lung, cervix carcinoma erythroleukemia, among other tissues. Regarding which tissues have MUC1 expression, here are a few articles citing expression in various tissues:
Cervix carcinoma, Pubmed ID: 15969018
Cervix carcinoma, and Erythroleukemia, Pubmed ID: 23186163
Lung, Pubmed ID: 8604237
Mammary carcinoma, Pubmed ID: 1697589, 11341784
Pancreatic carcinoma, Pubmed ID: 2394722

Boster Scientific Support

Answered: 2020-02-10

Question

We are currently using anti-MUC1 antibody PB9145 for human tissue, and we are well pleased with the IHC results. The species of reactivity given in the datasheet says human. Is it possible that the antibody can work on feline tissues as well?

O. Huang

Verified customer

Asked: 2019-11-26

Answer

The anti-MUC1 antibody (PB9145) has not been validated for cross reactivity specifically with feline tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in feline you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2019-11-26

Question

I am interested in using your anti-MUC1 antibody for nicotinamide salvaging studies. Has this antibody been tested with western blotting on ovary cancer tissue? We would like to see some validation images before ordering.

R. Brown

Verified customer

Asked: 2015-07-28

Answer

I appreciate your inquiry. This PB9145 anti-MUC1 antibody is tested on ovary cancer tissue. It is guaranteed to work for IHC in human. Our Boster guarantee will cover your intended experiment even if the sample type has not been be directly tested.

Boster Scientific Support

Answered: 2015-07-28

Order DetailsPrice
PB9145

100μg

$370
PB9145-10ug

10μg sample (liquid)

$99
PB9145-Biotin

100 μg Biotin conjugated

$570
PB9145-Cy3

100 μg Cy3 conjugated

$570
PB9145-Dylight488

100 μg Dylight488 conjugated

$570
PB9145-Dylight550

100 μg Dylight550 conjugated

$570
PB9145-Dylight594

100 μg Dylight594 conjugated

$570
PB9145-FITC

100 μg FITC conjugated

$570
PB9145-HRP

100 μg HRP conjugated

$570
PB9145-APC

100 μg APC conjugated

$670
PB9145-PE

100 μg PE conjugated

$670
PB9145-carrier-free

Carrier Free

$370

More conjugates/formats

Free Secondary Antibody

Choose an option to show lead time.
Get A Quote
Eddy test
In stock
Order Product
PB9145
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

Troubleshooting

troubleshooting-box-image

Download troubleshooting handbooks for IHC, Western blot and ELISA for FREE.

Download Free PDFs Now

Boster Guarantee

Guaranteed product quality

Guaranteed product quality

We promise all of our products perform as described in datasheets.