Anti-Myoglobin Mb Antibody (Monoclonal, MG-1)
Mouse IgG monoclonal antibody for Myoglobin, myoglobin (MB) detection. Tested with IHC-P in Human. No cross reactivity with other proteins. Cited in 2 publication(s).
Anti-Myoglobin Mb Antibody (Monoclonal, MG-1) Info At A Glance
Metadherin (MTDH) downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. MTDH activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Furthermore, MTDH promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a central component in tumor cell expansion. In addition, MTDH promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Metadherin also induces chemoresistance.
|Product Name||Anti-Myoglobin Mb Antibody (Monoclonal, MG-1)
See all Myoglobin primary antibodies, ELISA kits and proteins
|Storage & Handling||At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.|
|Description||Monoclonal clone# G2 antibody for Myoglobin/MB detection. Host: Mouse.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. Myoglobin/MB information: Molecular Weight: 17157 MW; .|
|Cite This Product||Anti-Myoglobin Mb Antibody (Monoclonal, MG-1) (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1062)|
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|Anti-Myoglobin Mb Antibody (Monoclonal, MG-1) may replace the following items: sc 101520|sc 101521|sc 107963 R|sc 107964 R|sc 130332|sc 130479|sc 13529|sc 139289|sc 139291|sc 18708|sc 20064|sc 25604|sc 25607|sc 25727|sc 390372|sc 393020|sc 53208|sc 53209|sc 65982|sc 74404|sc 7447|sc 7448|sc 7449|sc 74525|sc 8079|sc 8081|sc 8502.|
*Our Boster Guarantee covers the use of this product in the above tested applications.
*Innovating Scientists reward: if you test this antibody on a species or application not listed above and share with us your results, we will provide you a full credit to purchase Boster products.
|Related Products||Boster recommends HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P).
*Blocking peptide can be purchased at $50. Contact us for more information.
**Boster also offers various secondary antibodies for Immunoflourescecne and IHC. Take advantage of the buy 1 primary antibody get 1 secondary antibody for free promotion all year round.
|Immunogen||Purified human skeletal muscle myoglobin.|
|Cross Reactivity||No cross reactivity with other proteins|
Gene/Protein Basic Information For Mb (Source: Uniprot.org, NCBI)
|NCBI Gene Id||59108|
|Species Of This Entry||Rat|
|Alternative Names||Myoglobin|MB; MGC13548; Myoglobin; PVALB|
|Post Tranlational Modifications||Oxidation; Reduction; Phosphorylation; Cleavage; Methylation; Nitration; Ubiquitination; Acetylation; Demethylation; Carboxylation; Glycosylation; Biotinylation; Hydroxylation; Nitrosylation; Dephosphorylation; Acylation; Iodination; Deamination; Sulphation; Ribosylation|
|Gene Location||7q34, on Chromasome 7, gene sequence:|
*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".
Ontology For Mb (Source: Uniprot.org, NCBI)
|Protein Function||Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.|
|Related Diseases||Myocardial Infarction; Infarction; Acute Myocardial Infarction; Neoplasms; Malignant Neoplasms; Ischemia; Leprosy; Pain; Myocardial Ischemia; Chest Pain; Angina Pectoris; Heart Diseases; Coronary Heart Disease; Tuberculosis; Carcinoma; Malignant Neoplasm Of Breast; Medulloblastoma; Mammary Neoplasms|
|Related Pathways||Transport; Localization; Pathogenesis; Secretion; Cell Death; Methylation; Angiogenesis; Cell Proliferation; Virulence; Translation; Inflammatory Response; Metaphase; Cell Cycle; Cell Growth; Immune Response; Regeneration; Coagulation; Olfactory Learning; Vasoconstriction; Vasodilation|
|Background||Human myoglobin has 152 residues. Two myoglobin variants were found. The myoglobin locus mapped to 22q11-22q13. The myoglobin gene is about 10.5 kb long and contains two introns as in the case with hemoglobin genes. Myoglobin may serve a variety of functions in muscular oxygen supply, such as O(2) storage, facilitated O(2) diffusion, and myoglobin-mediated oxidative phosphorylation.|
|Scientific References||PMID: 22673903 by Lundby A., et al. Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.|
Our Boster Quality Guarantee for Anti-Myoglobin Mb Antibody (Monoclonal, MG-1) covers its use in the following applications.Immunohistochemistry(Paraffin-embedded Section), 1-2μg/ml, Human, By Heat
*The recommended dilution ratios/concentrations are for reference only and optimal dilutions/concentrations should be determined by the end user.
WB: Rat Skeletal Muscle Tissue Lysate
Boster provides comprehensive technical information for WB, IHC/IF/ICC, Flow Cytometry sample preparation protocols, assay protocols, troubleshooting tips and assay optimization tips.
- Western Blottting Resource Center
- Immunohistochemistry Resource Center
- Flow Cytometry Technical Resource Center
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Total number of citations: 2
|Xu H, He J, Zhang Y, Fan L, Zhao Y, Xu T, Nie Z, Li X, Huang Z, Lu B, Xu P. Carbohydr Polym. 2015 May 5;121:132-9. Doi: 10.1016/J.Carbpol.2014.12.057. Epub 2015 Jan 3. Synthesis And In Vitro Evaluation Of A Hyaluronic Acid-Quantum Dots-Melphalan C...||PubMed ID 25659681|
|Peng L, Yanjiao M, Ai-Guo W, Pengtao G, Jianhua L, Ju Y, Hongsheng O, Xichen Z. Biochem Biophys Res Commun. 2011 Jun 3;409(2):344-9. Doi: 10.1016/J.Bbrc.2011.05.021. Epub 2011 May 8. A Fine Balance Between Ccnl1 And Timp1 Contributes To The Develo...||PubMed ID 21586274|
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Note: sample size takes longer to process, average 5-7 days.
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