Product Info Summary
SKU: | M02496 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human |
Host: | Mouse |
Application: | IP, IHC-P, WB |
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Product info
Product Name
Anti-NTAL Purified LAT2 Monoclonal Antibody
SKU/Catalog Number
M02496
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-NTAL Purified LAT2 Monoclonal Antibody (Catalog# M02496). Tested in IP, WB, IHC-P application(s). This antibody reacts with Human.
Storage & Handling
Store at 2-8°C. Do not freeze.
Cite This Product
Anti-NTAL Purified LAT2 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M02496)
Host
Mouse
Contents
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Clonality
Monoclonal
Clone Number
NAP-03
Isotype
Mouse IgG2a
Immunogen
Peptide corresponding to aa 196-212 of human NTAL coupled to KLH. The antibody NAP-03 recognizes a defined intracellular epitope (aa 196-212) of human Non-T cell Activation Linker (NTAL), also known as LAB (linker of activated B cells), a 30 kDa transmembrane adaptor protein associating with lipid raft components in the plasma membrane of B cells, NK cells and myeloid cells.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
This antibody does not cross-react with Thy-1.1 alloantigen.
Reactive Species
M02496 is reactive to LAT2 in Human
Applications
M02496 is guaranteed for IP, IHC-P, WB Boster Guarantee
Observed Molecular Weight
42 kDa
Calculated molecular weight
26.55kDa
Background of NTAL
NTAL (non-T cell activation linker), also known as LAB (linker for activation of B cells), is a 30 kDa double-palmitoylated transmembrane adaptor protein expressed by B cells, NK cells, mast cells and macrophages. It is a negative regulator of early stages of BCR-dependent B cell signaling and serves as a negative regulator also in mast cells. However, in mast cells, NTAL also contributes to some activation processes, partially overlapping with LAT function.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Immunohistochemistry (paraffin sections): 5 μg/ml; positive tissue: tonsil, germinal center.
Western blotting: 1-2 μg/ml, incubation 60 min; positive control: RAMOS human lymphoma cell line; non-reducing conditions, 12% separating SDS-PAGE gel.
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For LAT2 (Source: Uniprot.org, NCBI)
Gene Name
LAT2
Full Name
Linker for activation of T-cells family member 2
Weight
26.55kDa
Alternative Names
LAB; LABWilliams-Beuren syndrome chromosomal region 15 protein; Linker for activation of B-cells; linker for activation of T cells family, member 2; linker for activation of T-cells family member 2; Membrane-associated adapter molecule; Non-T-cell activation linker; NTAL; NTALWilliams-Beuren syndrome chromosomal region 5 protein; WBS15; WBSCR15; WBSCR5; WBSCR5HSPC046; Williams-Beuren syndrome chromosome region 5; WSCR5 LAT2 HSPC046, LAB, NTAL, WBSCR15, WBSCR5, WSCR5 linker for activation of T cells family member 2 linker for activation of T-cells family member 2|Williams-Beuren syndrome chromosomal region 15 protein|Williams-Beuren syndrome chromosomal region 5 protein|linker for activation of B-cells|linker for activation of T cells, transmembrane adaptor 2|membrane-associated adapter molecule|non-T-cell activation linker
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on LAT2, check out the LAT2 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for LAT2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-NTAL Purified LAT2 Monoclonal Antibody (M02496)
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No publications found for M02496
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