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- Table of Contents
Facts about Linker for activation of T-cells family member 2.
Couples stimulation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2. .
Human | |
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Gene Name: | LAT2 |
Uniprot: | Q9GZY6 |
Entrez: | 7462 |
Belongs to: |
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No superfamily |
LAB; LABWilliams-Beuren syndrome chromosomal region 15 protein; Linker for activation of B-cells; linker for activation of T cells family, member 2; linker for activation of T-cells family member 2; Membrane-associated adapter molecule; Non-T-cell activation linker; NTAL; NTALWilliams-Beuren syndrome chromosomal region 5 protein; WBS15; WBSCR15; WBSCR5; WBSCR5HSPC046; Williams-Beuren syndrome chromosome region 5; WSCR5
Mass (kDA):
26.55 kDA
Human | |
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Location: | 7q11.23 |
Sequence: | 7; NC_000007.14 (74210006..74229834) |
Highly expressed in spleen, peripheral blood lymphocytes, and germinal centers of lymph nodes. Also expressed in placenta, lung, pancreas and small intestine. Present in B- cells, NK cells and monocytes. Absent from T-cells (at protein level).
Cell membrane; Single-pass type III membrane protein. Present in lipid rafts.
If you're trying to optimize a biochemical experiment, you may be wondering what the best choices are for Transporter-targeting probes and isotopes. We have provided optimization guides and tips to help you make the right choice. By following these tips, you can maximize your experiments. Read on to learn more! To learn more about this marker, you can also visit the Boster Bio user guide.
In recent years, many researchers have begun to study the potential of transporter-targeting drugs in the development of cancer vaccines. These drugs have the potential to deliver the tumor-specific antigen directly to the target tumor cells. Many of these therapies, however, are not yet proven and are costly. Boster Bio's transporter-targeting probes have recently been shown to have tremendous potential for cancer vaccine development.
The LAT2 marker is transporter-targeted and may be useful to identify RR-DTC metastases with radioiodine deficiency. These molecules may also be involved with cell metabolism. In addition, many transporter-targeting isotopes are routinely used in imaging TC.
An ELISA experiment can be performed in many ways. How to prepare the sample, what antibodies are used, and what blocking buffer is used are all important decisions. Boster Bio optimization suggestions can answer any questions. This guide can also help you optimize your experiment. Boster Bio can provide more information. You can also read common FAQs regarding the use of negative controls.
PMID: 11124535 by Doyle J.L., et al. Divergent human and mouse orthologs of a novel gene (WBSCR15/Wbscr15) reside within the genomic interval commonly deleted in Williams syndrome.
PMID: 11003705 by Martindale D.W., et al. Comparative genomic sequence analysis of the Williams syndrome region (LIMK1-RFC2) of human chromosome 7q11.23.