Disabled homolog 1 Antibodies

AND DAB1 ELISA kits, Disabled homolog 1 Proteins

Many biological assays use antibodies to detect Disabled homolog 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Disabled homolog 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Disabled homolog 1 antibodies...

We validate the specificity of these antibodies to Disabled homolog 1 by testing them on tissues known to express DAB1 positively and negatively. Browse below to find the DAB1 antibody that suites your experiment. We have 6 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for Disabled homolog 1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the DAB1 IHC Guide

DAB1 Infographic by Boster Bio

All DAB1 Products

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Product

Figures

Specificity

Applications

Price

Anti-Dab1 (Q226) Antibody

Western blot (WB) analysis of Dab1 (Q226) pAb at 1:500 dilution
Lane1:MCF-7 whole cell lysate(40ug)
Lane2:Hela whole cell lysate(40ug)
Lane3:SGC7901 whole cell lysate(40ug)
Lane4:PC12 whole cell lysate(40ug)
Lane5:The Brain tissue lysate of Mouse(40ug)

Immunohistochemistry (IHC) analyzes of Dab1 (Q226) pAb in paraffin-embedded human small intestine tissue at 1:100

Human, Mouse, Rat

IF, IHC, WB

$405
Cat # A03459
100ul

Dab1 (Phospho-Tyr232) Colorimetric Cell-Based ELISA Kit

Human, Mouse, Rat

ELISA

$540
Cat # EKC2383
1 kit, containing two 96-well plates and all necessary reagents

Dab1 Colorimetric Cell-Based ELISA Kit

Western blot analysis of extracts from HepG2/293 cells

Human, Mouse, Rat

ELISA

$480
Cat # EKC1162
1 kit, containing one 96-well plate and all necessary reagents

Anti-Phospho-Dab1 (Y232) Antibody

Western blot analysis of lysates from LOVO cells, using Dab1 (Phospho-Tyr232) Antibody

Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using Dab1 (Phospho-Tyr232) Antibody

Human, Mouse, Rat

ELISA, IF, WB

$380
Cat # A03459Y232
100ul

DAB1 (NM_021080) Human Over-expression Lysate

Human

$960
Cat # LS001600
20 µg, 100 µg

DAB1 (NM_021080) Human Recombinant Protein

Coomassie blue staining of purified DAB1 protein

$1062
Cat # PROTO75553
20 µg

DAB1 Overview

Facts about Disabled homolog 1.

DAB1 3D structure. Source: alphafold

Disabled homolog 1 (DAB1)

Adapter molecule functioning in neural development. May regulate SIAH1 activity.

Gene Information

Human
Gene Name:	DAB1
Uniprot:	O75553
Entrez:	1600

Family

Belongs to:

No superfamily

Alternative Names

disabled (Drosophila) homolog 1; disabled homolog 1 (Drosophila); disabled homolog 1

Molecular Weight

Mass (kDA):
63.775 kDA

Genomic Context


Human

Location:	1p32.2
Sequence:	1; NC_000001.11 (56994778..58250547, complement)

Tissue Specificity

Mainly expressed in brain.

Diseases

Nervousness
Alzheimer's Disease
Tissue Adhesions
Ataxia
Lissencephaly
Schizophrenia
Neoplasms
Malignant Neoplasms
Congenital Ectopia
Chimera Disorder
Congenital Neurologic Anomalies
Mental Disorders

Bipolar Disorder
Epilepsy
Dysplasia
Hydrocephalus
Malnutrition
Pain

Interacting Proteins

BHLHE40
C1orf94
CIART
DAZAP2
FAM168A

HMBOX1
HNRNPLL
HYAL3
KRTAP19-5
KRTAP19-7

KRTAP8-1
LGALS9B
LGALS9C
LNX1
MAGED1

MBNL1
MBNL3
NAF1
PIN1
POGZ

PPIG
PRR20C
RAMAC
RBFOX2
RHOXF2

SMAP2
STRBP
TCEA2
TCEANC
TMTC3

TOLLIP
VENTX
WDYHV1
ZC3H10
ZCCHC10

ZNF488

Pathways

Brain Development
Localization
Endocytosis
Cell Migration
Neurogenesis
Cell Proliferation
Secretion
Hyperphosphorylation
System Development
Neuron Migration
Clathrin-mediated Endocytosis
Cell Adhesion
Somal Translocation

Axon Guidance
Cell Motility
Lipid Binding
Dendrite Development
Innervation
Transport
Aging

PTMs

Phosphorylation
Cleavage

Ubiquitination
Biotinylation

Glycosylation

Research Areas

Growth and Development
Neuroscience
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DAB1

References

PMID: 9790777 by Lambert de Rouvroit C., et al. Cloning of human DAB1 and mapping to chromosome 1p31-p32.

PMID: 15272003 by Ranganathan S., et al. Serine and threonine phosphorylation of the low density lipoprotein receptor-related protein by protein kinase Calpha regulates endocytosis and association with adaptor molecules.