Product Info Summary
SKU: | A00012S824 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | WB |
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Product info
Product Name
Anti-TERT (phospho-S824) Antibody
SKU/Catalog Number
A00012S824
Size
100ul
Form
Liquid
Description
Boster Bio Anti-TERT (phospho-S824) Antibody catalog # A00012S824. Tested in WB applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-TERT (phospho-S824) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00012S824)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Clone Number
PI9-17
Isotype
IgG
Immunogen
Synthesized peptide derived from human TERT.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Weakly cross-reacts with dog p53.
Reactive Species
A00012S824 is reactive to TERT in Human, Mouse, Rat
Applications
A00012S824 is guaranteed for WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
126.997kDa
Background of TERT
Anti-Glycogen Synthase 1 pS641 antibody is validated by IHC, Western Blot and ELISA. Human muscle glycogen synthase (GS) is responsible for the biosynthesis of glycogen from phosphorylated glucose units. Mammalian liver and muscle contain GS consisting of four subunits with a total molecular weight of 360,000. GS is subject to regulation through both allosteric and covalent modification and occurs in two forms: the phosphorylated inactive form, and the dephosphorylated active form. GS is inactivated by the serine/threonine kinase called glycogen synthase kinase-3 that mainly functions to phosphorylate muscle glycogen synthase. This antibody is specific for the phosphorylated form of GS at S641. Phosphorylation of GS at S641 has been associated with Antiphospholipid Antibody Syndrome.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1000
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Western blotting validation for Anti-TERT (phospho-S824) Antibody A00012S824
Western blot (WB) analysis of TERT (phospho-S824) polyclonal antibody at 1:500 dilutionLane1:A549 whole cell lysate(40ug)
Lane2:H1792 whole cell lysate(40ug)
Lane3:HepG2 whole cell lysate(40ug)
Lane4:Panc1 whole cell lysate(40ug)
Lane5:K562 whole cell lysate(40ug)
Lane6: The Thymus tissue lysate of Rat(40ug)
Lane7: The Lung tissue lysate of Mouse(40ug)
Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
Protein Target Info & Infographic
Gene/Protein Information For TERT (Source: Uniprot.org, NCBI)
Gene Name
TERT
Full Name
Telomerase reverse transcriptase
Weight
126.997kDa
Superfamily
reverse transcriptase family
Alternative Names
EST2Telomerase-associated protein 2; hEST2; hTERT; TCS1EC 2.7.7.49; Telomerase catalytic subunit; telomerase reverse transcriptase; TERT; TP2HEST2; TRTEC 2.7.7 TERT CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT telomerase reverse transcriptase telomerase reverse transcriptase|telomerase catalytic subunit|telomerase-associated protein 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on TERT, check out the TERT Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for TERT: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-TERT (phospho-S824) Antibody (A00012S824)
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No publications found for A00012S824
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