Product Info Summary
SKU: | A02603-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IP, IF, ICC, WB |
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Product info
Product Name
Anti-Transcription factor SOX-11 SOX11 Antibody
SKU/Catalog Number
A02603-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Transcription factor SOX-11 SOX11 Antibody catalog # A02603-1. Tested in WB,ICC/IF,IP applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Transcription factor SOX-11 SOX11 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02603-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human NFATc4 around the phosphorylation site of S676.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A02603-1 is reactive to SOX11 in Human, Mouse, Rat
Applications
A02603-1 is guaranteed for IP, IF, ICC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
46.679kDa
Background of SOX11
p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcellular distribution.
Tsai L.-H., Nature 371:419-423(1994).
Patrick G.N., Nature 402:615-622(1999).
Kesavapany S., J. Neurosci. 24:4421-4431(2004).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1,000
ICC: 1:50-1:200
Validation Images & Assay Conditions
Click image to see more details
Figure 1. Immunocytochemistry staining of SOX11 using Anti-Transcription factor SOX-11 SOX11 Antibody (A02603-1).
ICC staining SOX11 in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehydeClick image to see more details
Figure 2. Immunocytochemistry staining of SOX11 using Anti-Transcription factor SOX-11 SOX11 Antibody (A02603-1).
ICC staining SOX11 in N2A cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehydeProtein Target Info & Infographic
Gene/Protein Information For SOX11 (Source: Uniprot.org, NCBI)
Gene Name
SOX11
Full Name
Transcription factor SOX-11
Weight
46.679kDa
Alternative Names
SOX11; SRY (sex determining region Y)-box 11; SRY (sex-determining region Y)-box 11; SRY-related HMG-box gene 11; transcription factor SOX-11 SOX11 CSS9, MRD27 SRY-box transcription factor 11 transcription factor SOX-11|SRY (sex-determining region Y)-box 11|SRY-box 11|SRY-related HMG-box gene 11
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on SOX11, check out the SOX11 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for SOX11: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Transcription factor SOX-11 SOX11 Antibody (A02603-1)
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No publications found for A02603-1
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