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- Table of Contents
ACE2 Antibodies
AND ACE2 ELISA kits, ACE2 Proteins
Many biological assays use antibodies to detect ACE2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ACE2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ACE2 antibodies...
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ACE2 Infographic by Boster Bio
All ACE2 Products
Product
Figures
Specificity
Applications
Price
Mouse ACE2 ELISA Kit PicoKine®
3 Citations 4 Q&As
Mouse
ELISA
$499
Cat # EK1188
96 wells/kit, with removable strips.
Cat # EK1188
96 wells/kit, with removable strips.
Anti-ACE2 Rabbit Monoclonal Antibody
4 Citations 5 Q&As
Human, Mouse, Rat
IP, IF, IHC, ICC, WB
$370
Cat # M00756
100 μl
Cat # M00756
100 μl
Human
ELISA, IP, IF, IHC, WB
$146
Cat # M00756-2
20μL, 40μL, 100μL, 200μL
Cat # M00756-2
20μL, 40μL, 100μL, 200μL
ACE2 Overview
Facts about Angiotensin-converting enzyme 2.
Angiotensin-converting enzyme 2 (ACE2)
Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin- 13 and dynorphin-13 with high efficiency.
May be an important regulator of heart function. .
Gene Information
| Human | |
|---|---|
| Gene Name: | ACE2 |
| Uniprot: | Q9BYF1 |
| Entrez: | 59272 |
Family
| Belongs to: |
|---|
| peptidase M2 family |
Alternative Names
ACE2; ACE-2; ACEH; ACEHangiotensin I converting enzyme 2; ACE-related carboxypeptidase; angiotensin I converting enzyme (peptidyl-dipeptidase A) 2; angiotensin-converting enzyme 2; Angiotensin-converting enzyme homolog; DKFZp434A014; EC 3.4.17; EC 3.4.17.23; Metalloprotease MPROT15
Molecular Weight
Mass (kDA):
92.463 kDA
Genomic Context
| Human | |
|---|---|
| Location: | Xp22.2 |
| Sequence: | X; NC_000023.11 (15494520..15602158, complement) |
Tissue Specificity
Expressed in endothelial cells from small and large arteries, and in arterial smooth muscle cells. Expressed in lung alveolar epithelial cells, enterocytes of the small intestine, Leydig cells and Sertoli cells (at protein level). Expressed in heart, kidney, testis, and gastrointestinal system.
Subcellular Localizations
[Processed angiotensin-converting enzyme 2]: Secreted.; Cell membrane; Single-pass type I membrane protein. Cytoplasm. Detected in both cell membrane and cytoplasm in neurons.
Diseases
- Hypertensive Disease
- Severe Acute Respiratory Syndrome
- Kidney Diseases
- Cardiovascular Diseases
- Hypertrophy
- Fibrosis
- Diabetes Mellitus
- Heart Failure
- Diabetic Nephropathy
- Inflammation
- Injury To Kidney
- Myocardial Infarction
Pathways
- Pathogenesis
- Localization
- Cell Cycle
- Vasoconstriction
- Mitosis
- Cell Proliferation
- Transport
- Regulation Of Blood Pressure
- Excretion
- Membrane Fusion
- Cell Division
- Cytokinesis
- Virulence
PTMs
- Cleavage
- Phosphorylation
- Glycosylation
- Deglycosylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ACE2
bosterbio.com/bosterbio-gene-info-cards/ACE2
References
PMID: 10969042 by Donoghue M., et al. A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9.
PMID: 10924499 by Tipnis S.R., et al. A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase.
3 Publications of Boster ACE2 Antibodies & ELISA Kits
- PubMed ID: 10.1080/10641963.2018.1529782, Serum concentration of renin-angiotensin system components in association with A...
- PubMed ID: -, Gu J,Yin J,Zhang M,Li J,Wu Y,Chen J,Miao H.Study on the Clinical Significance of...
- PubMed ID: 29184499, Chiang MH, Liang CJ, Liu CW, Pan BJ, Chen WP, Yang YF, Lee IT, Tsai JS, Lee CW, ...
*More publications can be found for each product on its corresponding product page