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- Table of Contents
Alpha-actinin-2 Antibodies
AND ACTN2 ELISA kits, Alpha-actinin-2 Proteins
Many biological assays use antibodies to detect Alpha-actinin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Alpha-actinin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Alpha-actinin-2 antibodies...
Designing a Western blot for Alpha-actinin-2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ACTN2 Western Blot GuideACTN2 Infographic by Boster Bio
All ACTN2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A03673-1
100 μg/vial
Cat # A03673-1
100 μg/vial
Anti-ACTN2 Rabbit Monoclonal Antibody
1 Citations
Human, Mouse, Rat
IP, IHC, WB
$370
Cat # M03673
100 μl
Cat # M03673
100 μl
Human, Mouse, Rat
IP, IHC, WB
$370
Cat # M03673-1
100 μl/vial
Cat # M03673-1
100 μl/vial
Human, Mouse, Rat
ELISA
$480
Cat # EKC1712
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1712
1 kit, containing one 96-well plate and all necessary reagents
ACTN2 Overview
Facts about Alpha-actinin-2.
Alpha-actinin-2 (ACTN2)
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | ACTN2 |
| Uniprot: | P35609 |
| Entrez: | 88 |
Family
| Belongs to: |
|---|
| alpha-actinin family |
Alternative Names
Actinin alpha 2; actinin, alpha 2; Actinin-a2; ACTN2; alpha Actinin 2; alpha-Actinin 2; Alpha-actinin skeletal muscle isoform 2; Alpha-Actinin Skeletal Muscle; Alpha-Actinin-2; CMD1AA; F-actin cross-linking protein
Molecular Weight
Mass (kDA):
103.854 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q43 |
| Sequence: | 1; NC_000001.11 (236686454..236764631) |
Tissue Specificity
Expressed in both skeletal and cardiac muscle.
Subcellular Localizations
Cytoplasm, myofibril, sarcomere, Z line. Colocalizes with MYOZ1 and FLNC at the Z-lines of skeletal muscle.
Diseases
- Cardiomyopathies
- Myopathy
- Dystrophy
- Hypertrophy
- Muscular Dystrophy
- Muscular Dystrophy, Duchenne
- Myopathies, Nemaline
- Heart Failure
- Hypertrophic Cardiomyopathy
- Cardiomyopathy, Dilated
- Neuromuscular Diseases
- Congenital Myopathy (disorder)
- Malignant Neoplasms
Pathways
- Localization
- Transport
- Cell Differentiation
- Protein Phosphorylation
- Cell Adhesion
- Muscle Cell Differentiation
- Proteolysis
- Muscle Contraction
- Replicative Senescence
- Translation
- Cell Cycle
- Cell Motility
- Lipid Transport
PTMs
- Phosphorylation
- Biotinylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ACTN2
bosterbio.com/bosterbio-gene-info-cards/ACTN2
References
PMID: 1339456 by Beggs A.H., et al. Cloning and characterization of two human skeletal muscle alpha- actinin genes located on chromosomes 1 and 11.
PMID: 10548523 by Tiso N., et al. Fine mapping and genomic structure of ACTN2, the human gene coding for the sarcomeric isoform of alpha-actinin-2, expressed in skeletal and cardiac muscle.
3 Publications of Boster Alpha-actinin-2 Antibodies & ELISA Kits
- PubMed ID: 24551180, Similar to Spironolactone, Oxymatrine Is Protective in Aldosterone-Induced Cardi...
- PubMed ID: 25120772, Effects of BMSCs interactions with adventitial fibroblasts in transdifferentiati...
- PubMed ID: 23867886, Li H, Tang M, Liang H, Li Y, Wang J, Song Y, Zheng Y, Xi J, Zhang J, Hescheler J...
*More publications can be found for each product on its corresponding product page