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Adenosine deaminase Antibodies
AND ADA ELISA kits, Adenosine deaminase Proteins
Many biological assays use antibodies to detect Adenosine deaminase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Adenosine deaminase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Adenosine deaminase antibodies...
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ADA Infographic by Boster Bio
All ADA Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # EK1446
96 wells/kit, with removable strips.
Cat # EK1446
96 wells/kit, with removable strips.
Anti-ADA Antibody Picoband®
17 Q&As
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # PB9914
100 μg/vial
Cat # PB9914
100 μg/vial
Anti-ADA Antibody Picoband®
1 Citations 19 Q&As
Mouse, Rat
ELISA, IHC, WB
$370
Cat # A00866-1
100 μg/vial
Cat # A00866-1
100 μg/vial
Anti-ADA Antibody Picoband®
1 Citations 16 Q&As
Mouse, Rat
IHC, WB, ELISA (Cap)
$370
Cat # A00866-2
100 μg/vial
Cat # A00866-2
100 μg/vial
Human
Flow Cytometry, IHC, WB
$370
Cat # M00866
100 μg/vial
Cat # M00866
100 μg/vial
Enzyme Activity, SDS-PAGE
$265
Cat # PROTP00813
Starting from 10ug
Cat # PROTP00813
Starting from 10ug
ADA Overview
Facts about Adenosine deaminase.
Adenosine deaminase (ADA)
Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine (PubMed:8452534, PubMed:16670267). Plays an essential role in purine metabolism and in adenosine homeostasis.
Modulates signaling by extracellular adenosine, and so leads indirectly to cellular signaling events. Its interaction with DPP4 modulates lymphocyte- epithelial cell adhesion (PubMed:11772392).
Gene Information
| Human | |
|---|---|
| Gene Name: | ADA |
| Uniprot: | P00813 |
| Entrez: | 100 |
Family
| Belongs to: |
|---|
| metallo-dependent hydrolases superfamily |
Alternative Names
ADA; ADA1; adenine deaminase; Adenosine aminohydrolase; Adenosine Deaminase; EC 3.5.4.4
Molecular Weight
Mass (kDA):
40.764 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 20q13.12 |
| Sequence: | 20; NC_000020.11 (44619519..44651758, complement) |
Tissue Specificity
Found in all tissues, occurs in large amounts in T-lymphocytes (PubMed:20959412). Expressed at the time of weaning in gastrointestinal tissues.
Subcellular Localizations
Cell membrane; Peripheral membrane protein; Extracellular side. Cell junction. Cytoplasmic vesicle lumen. Cytoplasm. Lysosome. Colocalized with DPP4 at the cell surface.
Diseases
- Diabetes Mellitus
- Immunologic Deficiency Syndromes
- Diabetes Mellitus, Non-insulin-dependent
- Tuberculosis
- Hiv Infections
- Severe Combined Immunodeficiency
- Adenosine Deaminase Deficiency
- Congenital Combined Immunodeficiency
- Malignant Neoplasms
- Pleural Effusion Disorder
- Acquired Immunodeficiency Syndrome
- Impaired Glucose Tolerance
Pathways
- Dna Repair
- Pathogenesis
- Immune Response
- Secretion
- Localization
- Transport
- Methylation
- Cell Proliferation
- Hypersensitivity
- Cell Death
- Aging
- Insulin Secretion
- Translation
PTMs
- Methylation
- Deamination
- Glycosylation
- Phosphorylation
- Cleavage
- Acetylation
- Oxidation
- Dephosphorylation
- Carboxylation
- Nitration
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ADA
bosterbio.com/bosterbio-gene-info-cards/ADA
References
PMID: 6090454 by Daddona P.E., et al. Human adenosine deaminase. cDNA and complete primary amino acid sequence.
PMID: 6546794 by Wiginton D.A., et al. Sequence of human adenosine deaminase cDNA including the coding region and a small intron.