ARPC5 Antibodies

AND ARPC5 ELISA kits, ARPC5 Proteins

Many biological assays use antibodies to detect ARPC5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ARPC5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ARPC5 antibodies...

We validate the specificity of these antibodies to ARPC5 by testing them on tissues known to express ARPC5 positively and negatively. Browse below to find the ARPC5 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ARPC5 Infographic by Boster Bio

All ARPC5 Products

Product

Figures

Specificity

Applications

Price

Anti-p16 ARC ARPC5 Rabbit Monoclonal Antibody

6 Q&As

Human, Mouse, Rat

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # M02096
100 μl

p16 ARC (ARPC5) (NM_005717) Human Recombinant Protein

$1249
Cat # PROTO15511
20 µg

Anti-ARPC5 Antibody (Center)

Human, Mouse, Rat

IF, WB

$298
Cat # M02096-1
50 µl

p16 ARC (ARPC5) (NM_005717) Human Over-expression Lysate

Human

$628
Cat # LS010092
100 µg

ARPC5 Overview

Facts about Actin-related protein 2/3 complex subunit 5.

ARPC5 3D structure. Source: alphafold

Actin-related protein 2/3 complex subunit 5 (ARPC5)

Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation- promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079).

Besides its function in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:29925947). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by encouraging nuclear actin polymerization, leading to drive motility of double- strand breaks (DSBs) (PubMed:29925947).

Gene Information

Human
Gene Name:	ARPC5
Uniprot:	O15511
Entrez:	10092

Family

Belongs to:

ARPC5 family

Alternative Names

actin related protein 2/3 complex, subunit 5, 16kDa; ARC16subunit 5 (16 kD); MGC88523

Molecular Weight

Mass (kDA):
16.32 kDA

Genomic Context


Human

Location:	1q25.3
Sequence:	1; NC_000001.11 (183620846..183635783, complement)

Subcellular Localizations

Cytoplasm, cytoskeleton. Cell projection. Nucleus.

Diseases

Malignant Squamous Cell Neoplasm
Carcinoma
Malignant Neoplasms
Neoplasms
Wiskott-aldrich Syndrome
Cell Invasion
Cell Transformation, Neoplastic
Lung Neoplasms
Rhabdomyosarcoma
Head And Neck Carcinoma
Cholecystolithiasis

Enterovirus Infections
Neoplasm Invasiveness
Carcinogenesis
Head And Neck Neoplasms
Dental Plaque
Invasive Malignant Neoplasm

Pathways

Actin Nucleation
Transport
Endocytosis
Clathrin-mediated Endocytosis
Cell Proliferation
Smooth Muscle Contraction
Cell Migration
Muscle Contraction
Spermatid Differentiation
Spermatogenesis
Translation

Locomotion
Lipid Homeostasis
Cell Differentiation
Cell Morphogenesis
Pathogenesis
Oncogenesis

PTMs

Acetylation

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ARPC5

References

PMID: 9230079 by Welch M.D., et al. The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly.

PMID: 9359840 by Machesky L.M., et al. Mammalian actin-related protein 2/3 complex localizes to regions of lamellipodial protrusion and is composed of evolutionarily conserved proteins.