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- Table of Contents
Angiopoietin-1 Antibodies
AND ANGPT1 ELISA kits, Angiopoietin-1 Proteins
Many biological assays use antibodies to detect Angiopoietin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Angiopoietin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Angiopoietin-1 antibodies...
Designing a Western blot for Angiopoietin-1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ANGPT1 Western Blot GuideANGPT1 Infographic by Boster Bio
All ANGPT1 Products
Product
Figures
Specificity
Applications
Price
Mouse Angiopoietin-1 ELISA Kit PicoKine®
10 Citations
Mouse
ELISA
$450
Cat # EK1296
96 wells/kit, with removable strips.
Cat # EK1296
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # EK0559
96 wells/kit, with removable strips.
Cat # EK0559
96 wells/kit, with removable strips.
Rat Angiopoietin-1 ELISA Kit PicoKine®
4 Citations
Rat
ELISA
$499
Cat # EK1295
96 wells/kit, with removable strips.
Cat # EK1295
96 wells/kit, with removable strips.
Human
ELISA
$500
Cat # EZ0559
For 5 plates, 96 wells each
Cat # EZ0559
For 5 plates, 96 wells each
Human
ELISA
$499
Cat # FEK0559
96 wells/kit, with removable strips.
Cat # FEK0559
96 wells/kit, with removable strips.
Mouse
ELISA
$500
Cat # EZ1296
For 5 plates, 96 wells each
Cat # EZ1296
For 5 plates, 96 wells each
Mouse
ELISA
$499
Cat # FEK1296
96 wells/kit, with removable strips.
Cat # FEK1296
96 wells/kit, with removable strips.
Rat
ELISA
$500
Cat # EZ1295
For 5 plates, 96 wells each
Cat # EZ1295
For 5 plates, 96 wells each
Rat
ELISA
$499
Cat # FEK1295
96 wells/kit, with removable strips.
Cat # FEK1295
96 wells/kit, with removable strips.
Human, Rat
WB
$370
Cat # M00853
100 μl
Cat # M00853
100 μl
Human, Mouse, Rat
IHC, WB
$523
Cat # M00853-1
100 µl
Cat # M00853-1
100 µl
Human
$960
Cat # LS000284
20 µg, 100 µg
Cat # LS000284
20 µg, 100 µg
ANGPT1 Overview
Facts about Angiopoietin-1.
Angiopoietin-1 (ANGPT1)
Binds and activates TEK/TIE2 receptor by causing its dimerization and tyrosine phosphorylation. Plays an essential role in the regulation of angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence.
Required for normal angiogenesis and heart development during embryogenesis. After birth, activates or inhibits angiogenesis, depending on the context.
Gene Information
| Human | |
|---|---|
| Gene Name: | ANGPT1 |
| Uniprot: | Q15389 |
| Entrez: | 284 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
AGP1; AGPT; Ang1; ANG-1; angiopoietin 1; Angiopoietin-1; ANGPT1; KIAA0003
Molecular Weight
Mass (kDA):
57.513 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 8q23.1 |
| Sequence: | 8; NC_000008.11 (107249482..107497918, complement) |
Subcellular Localizations
Secreted.
Diseases
- Tumor Angiogenesis
- Pathologic Neovascularization
- Neoplasms
- Malignant Neoplasms
- Multiple Endocrine Neoplasia Type 1
- Neoplasm Metastasis
- Inflammation
- Carcinoma
- Ischemia
- Tissue Adhesions
- Hypoxia
- Retinal Diseases
Interacting Proteins
- MAPK8IP2
Pathways
- Angiogenesis
- Cell Proliferation
- Localization
- Pathogenesis
- Vasculogenesis
- Secretion
- Cell Adhesion
- Cell Growth
- Endothelial Cell Proliferation
- Tube Formation
- Wound Healing
- Regeneration
- Cell Migration
PTMs
- Phosphorylation
- Cleavage
Research Areas
- Angiogenesis
- Cancer
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ANGPT1
bosterbio.com/bosterbio-gene-info-cards/ANGPT1
References
PMID: 8980223 by Davis S., et al. Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning.
PMID: 9204896 by Maisonpierre P.C., et al. Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis.
23 Publications of Boster Angiopoietin-1 Antibodies & ELISA Kits
- PubMed ID: PMID:25973012, Biocompatibility of porcine small intestinal submucosa and rat endothelial proge...
- PubMed ID: 10.3980/j.issn.2222-3959.2014.04.11, Effects of laser photocoagulation on serum angiopoietin-1, angiopoietin-2, angio...
- PubMed ID: 10.3389/fnins.2019.01306, Viability and Contractility of Rat Brain Pericytes in Conditions That Mimic Stro...
- PubMed ID: 10.1038/s41598-021-91499-3, Whole blood transfusion improves vascular integrity and increases survival in ar...
- PubMed ID: 10.1038/s41598-017-02216-y, Angiopoietin-1 enhances neutrophil chemotaxis in vitro and migration in vivo thr...
- PubMed ID: 10.1016/j.leukres.2017.01.017, Simvastatin ameliorates graft-vs-host disease by regulating angiopoietin-1 and a...
- PubMed ID: 10.1016/j.cellsig.2020.109812, Blocking exosomal miRNA-153-3p derived from bone marrow mesenchymal stem cells a...
- PubMed ID: 10.1007/s10735-019-09810-6, Osteogenic and angiogenic characterization of mandible and femur osteoblasts
- PubMed ID: 10.1002/brb3.1013, Rat astrocytes during anoxia: Secretome profile of cytokines and chemokines
- PubMed ID: 10.1002/brb3.1013, Rat astrocytes during anoxia: Secretome profile of cytokines and chemokines
- PubMed ID: 10.1002/brb3.1013, Rat astrocytes during anoxia: Secretome profile of cytokines and chemokines
- PubMed ID: , Platelets docking to VWF prevent leaks during leukocyte extravasation by stimula...
- PubMed ID: -, Zhang, P., Peng, J., Ren, Y., Zheng, H., & Yan, H.(2021).Dexmedetomidine protect...
- PubMed ID: 32391293, Ruan Y,Dong W,Kang L,Lei X,Zhang R,Wang F,Zhu X.The Changes of Twist1 Pathway in...
- PubMed ID: 28122283 , Simvastatin ameliorates graft-vs-host disease by regulating angiopoietin-1 and a...
- PubMed ID: 20043346, Cytocompatibility of regenerated silk fibroin film: a medical biomaterial applic...
- PubMed ID: 25973012, Biocompatibility of porcine small intestinal submucosa and rat endothelial proge...
- PubMed ID: 28539655, Angiopoietin-1 enhances neutrophil chemotaxis in vitro and migration in vivo thr...
- PubMed ID: 25161936, Effects of laser photocoagulation on serum angiopoietin-1, angiopoietin-2, angio...
- PubMed ID: 23554691, Hypoxic response elements and Tet-On advanced double-controlled systems regulate...
- PubMed ID: 28947667, Schlosser K, Taha M, Deng Y, McIntyre LA, Mei SHJ, Stewart DJ. Thorax. 2018 Mar;...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page