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- Table of Contents
Catenin alpha-1 Antibodies
AND CTNNA1 ELISA kits, Catenin alpha-1 Proteins
Many biological assays use antibodies to detect Catenin alpha-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Catenin alpha-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Catenin alpha-1 antibodies...
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CTNNA1 Infographic by Boster Bio
All CTNNA1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, IHC-F, ICC, WB
$370
Cat # PB9137
100 μg/vial
Cat # PB9137
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M01617
100 μl
Cat # M01617
100 μl
Human, Mouse, Rat
ELISA
$480
Cat # EKC1090
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1090
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # M01617-1
100 μg/vial
Cat # M01617-1
100 μg/vial
Human, Mouse, Rat
ELISA, IF, IHC
$380
Cat # A01617S641
100ul
Cat # A01617S641
100ul
Human
$628
Cat # LS001495
20 µg, 100 µg
Cat # LS001495
20 µg, 100 µg
CTNNA1 Overview
Facts about Catenin alpha-1.
Catenin alpha-1 (CTNNA1)
Associates with the cytoplasmic domain of an assortment of cadherins. The institution of catenins to cadherins produces a complex which is associated with the actin filament network, and which appears to be of primary importance for cadherins cell-adhesion properties.
Can associate with both E- and N-cadherins. Originally thought to be a stable part of E-cadherin/catenin adhesion complexes and also to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions.
Gene Information
| Human | |
|---|---|
| Gene Name: | CTNNA1 |
| Uniprot: | P35221 |
| Entrez: | 1495 |
Family
| Belongs to: |
|---|
| vinculin/alpha-catenin family |
Alternative Names
Alpha E-catenin; alpha-catenin; alpha-E-catenin; alphaE-catenin; cadherin-associated protein; CAP102; catenin (cadherin-associated protein), alpha 1 (102kD); catenin (cadherin-associated protein), alpha 1, 102kDa; catenin alpha-1; FLJ36832; FLJ52416; Renal carcinoma antigen NY-REN-13
Molecular Weight
Mass (kDA):
100.071 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q31.2 |
| Sequence: | 5; NC_000005.10 (138753386..138935034) |
Tissue Specificity
Expressed ubiquitously in normal tissues.
Subcellular Localizations
[Isoform 1]: Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction. Found at cell-cell boundaries and probably at cell-matrix boundaries.; [Isoform 3]: Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Diseases
- Tissue Adhesions
- Neoplasms
- Malignant Neoplasms
- Carcinoma
- Neoplasm Metastasis
- Cell Invasion
- Neoplasm Invasiveness
- Adenocarcinoma
- Mammary Neoplasms
- Malignant Paraganglionic Neoplasm
- Malignant Neoplasm Of Breast
- Colonic Neoplasms
- Malignant Tumor Of Colon
Interacting Proteins
- APC
- ARRB2
- CDH1
- CEP350
- CTNNB1
- ECT2
- EGFR
- JUP
- LIMA1
- NFKBIA
Pathways
- Cell-cell Adhesion
- Cell Adhesion
- Localization
- Cell Growth
- Cell Proliferation
- Pathogenesis
- Methylation
- Dedifferentiation
- Cell Motility
- Cell Migration
- Cell Differentiation
- Cellular Localization
PTMs
- Phosphorylation
- Methylation
- Cleavage
- Biotinylation
Research Areas
- Cancer
- Cell Biology
- Cellular Markers
- Core ESC-Like Genes
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CTNNA1
bosterbio.com/bosterbio-gene-info-cards/CTNNA1
References
PMID: 8404069 by Furukawa Y., et al. Structure, expression and chromosome assignment of the human catenin (cadherin-associated protein) alpha 1 gene (CTNNA1).
PMID: 8323564 by Oda T., et al. Cloning of the human alpha-catenin cDNA and its aberrant mRNA in a human cancer cell line.
3 Publications of Boster Catenin alpha-1 Antibodies & ELISA Kits
- PubMed ID: 10.1038/srep23775, TALENs-directed knockout of the full-length transcription factor Nrf1α that rep...
- PubMed ID: 15484291, Prognostic and clinicopathological features of E-cadherin, ?-catenin, ?-catenin,...
- PubMed ID: 27065079, TALENs-directed?knockout?of the?full-length?transcription?factor?Nrf1? that?repr...
*More publications can be found for each product on its corresponding product page