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- Table of Contents
Catenin alpha-1 Antibodies
AND CTNNA1 ELISA kits, Catenin alpha-1 Proteins
Many biological assays use antibodies to detect Catenin alpha-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Catenin alpha-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Catenin alpha-1 antibodies...
Designing a Western blot for Catenin alpha-1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CTNNA1 Western Blot GuideCTNNA1 Infographic by Boster Bio
All CTNNA1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # M01617-1
100 μg/vial
Cat # M01617-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, IHC-F, ICC, WB
$370
Cat # PB9137
100 μg/vial
Cat # PB9137
100 μg/vial
Human, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01649-3
100 μg/vial
Cat # M01649-3
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M01617
100 μl
Cat # M01617
100 μl
Human, Mouse, Rat
ELISA
$480
Cat # EKC1090
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1090
1 kit, containing one 96-well plate and all necessary reagents
Human
$628
Cat # LS001495
20 µg, 100 µg
Cat # LS001495
20 µg, 100 µg
Human, Mouse, Rat
ELISA, IF, IHC
$380
Cat # A01617S641
100ul
Cat # A01617S641
100ul
CTNNA1 Overview
Facts about Catenin alpha-1.
Catenin alpha-1 (CTNNA1)
Associates with the cytoplasmic domain of an assortment of cadherins. The institution of catenins to cadherins produces a complex which is associated with the actin filament network, and which appears to be of primary importance for cadherins cell-adhesion properties.
Can associate with both E- and N-cadherins. Originally thought to be a stable part of E-cadherin/catenin adhesion complexes and also to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions.
Gene Information
| Human | |
|---|---|
| Gene Name: | CTNNA1 |
| Uniprot: | P35221 |
| Entrez: | 1495 |
Family
| Belongs to: |
|---|
| vinculin/alpha-catenin family |
Alternative Names
Alpha E-catenin; alpha-catenin; alpha-E-catenin; alphaE-catenin; cadherin-associated protein; CAP102; catenin (cadherin-associated protein), alpha 1 (102kD); catenin (cadherin-associated protein), alpha 1, 102kDa; catenin alpha-1; FLJ36832; FLJ52416; Renal carcinoma antigen NY-REN-13
Molecular Weight
Mass (kDA):
100.071 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q31.2 |
| Sequence: | 5; NC_000005.10 (138753386..138935034) |
Tissue Specificity
Expressed ubiquitously in normal tissues.
Subcellular Localizations
[Isoform 1]: Cytoplasm, cytoskeleton. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction. Found at cell-cell boundaries and probably at cell-matrix boundaries.; [Isoform 3]: Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Diseases
- Tissue Adhesions
- Neoplasms
- Malignant Neoplasms
- Carcinoma
- Neoplasm Metastasis
- Cell Invasion
- Neoplasm Invasiveness
- Adenocarcinoma
- Mammary Neoplasms
- Malignant Paraganglionic Neoplasm
- Malignant Neoplasm Of Breast
- Colonic Neoplasms
- Malignant Tumor Of Colon
Interacting Proteins
- APC
- ARRB2
- CDH1
- CEP350
- CTNNB1
- ECT2
- EGFR
- JUP
- LIMA1
- NFKBIA
Pathways
- Cell-cell Adhesion
- Cell Adhesion
- Localization
- Cell Growth
- Cell Proliferation
- Pathogenesis
- Methylation
- Dedifferentiation
- Cell Motility
- Cell Migration
- Cell Differentiation
- Cellular Localization
PTMs
- Phosphorylation
- Methylation
- Cleavage
- Biotinylation
Research Areas
- Cancer
- Cell Biology
- Cellular Markers
- Core ESC-Like Genes
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CTNNA1
bosterbio.com/bosterbio-gene-info-cards/CTNNA1
References
PMID: 8404069 by Furukawa Y., et al. Structure, expression and chromosome assignment of the human catenin (cadherin-associated protein) alpha 1 gene (CTNNA1).
PMID: 8323564 by Oda T., et al. Cloning of the human alpha-catenin cDNA and its aberrant mRNA in a human cancer cell line.
3 Publications of Boster Catenin alpha-1 Antibodies & ELISA Kits
- PubMed ID: 10.1038/srep23775, TALENs-directed knockout of the full-length transcription factor Nrf1α that rep...
- PubMed ID: 15484291, Prognostic and clinicopathological features of E-cadherin, ?-catenin, ?-catenin,...
- PubMed ID: 27065079, TALENs-directed?knockout?of the?full-length?transcription?factor?Nrf1? that?repr...
*More publications can be found for each product on its corresponding product page