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- Table of Contents
Cathepsin E Antibodies
AND CTSE ELISA kits, Cathepsin E Proteins
Many biological assays use antibodies to detect Cathepsin E, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cathepsin E in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cathepsin E antibodies...
Designing a Western blot for Cathepsin E? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CTSE Western Blot GuideCTSE Infographic by Boster Bio
All CTSE Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$499
Cat # FEK1306
96 wells/kit, with removable strips.
Cat # FEK1306
96 wells/kit, with removable strips.
Human
ELISA
$499
Cat # EK1306
96 wells/kit, with removable strips.
Cat # EK1306
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # EK2128
96 wells/kit, with removable strips.
Cat # EK2128
96 wells/kit, with removable strips.
CTSE Overview
Facts about Cathepsin E.
Cathepsin E (CTSE)
May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation.
May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CTSE |
| Uniprot: | P14091 |
| Entrez: | 1510 |
Family
| Belongs to: |
|---|
| peptidase A1 family |
Alternative Names
CATE; Cathepsin E; CTSE; EC 3.4.23; EC 3.4.23.34; erythrocyte membrane aspartic proteinase; slow-moving proteinase
Molecular Weight
Mass (kDA):
42.794 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1q32.1 |
| Sequence: | 1; NC_000001.11 (206009264..206023899, complement) |
Tissue Specificity
Expressed abundantly in the stomach, the Clara cells of the lung and activated B-lymphocytes, and at lower levels in lymph nodes, skin and spleen. Not expressed in resting B- lymphocytes.
Subcellular Localizations
Endosome. The proenzyme is localized to the endoplasmic reticulum and Golgi apparatus, while the mature enzyme is localized to the endosome.
Diseases
- Malignant Neoplasms
- Neoplasms
- Adenocarcinoma
- Carcinoma
- Adenoma
- Pancreatic Neoplasm
- Neoplasm Invasiveness
- Malignant Neoplasm Of Urinary Bladder
- Gastric Adenocarcinoma
- Pancreatic Ductal Adenocarcinoma
- Pancreatitis, Chronic
- Colorectal Neoplasms
Pathways
- Localization
- Sensitization
- Cell Proliferation
- Induction Of Apoptosis
- Cell Death
- Innate Immune Response
- Immune Response
- Glycosylation
- Angiogenesis
PTMs
- Glycosylation
Research Areas
- Adaptive Immunity
- Immunology
- Innate Immunity
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CTSE
bosterbio.com/bosterbio-gene-info-cards/CTSE
References
PMID: 2674141 by Azuma T., et al. Human gastric cathepsin E. Predicted sequence, localization to chromosome 1, and sequence homology with other aspartic proteinases.
PMID: 1370478 by Azuma T., et al. Human gastric cathepsin E gene. Multiple transcripts result from alternative polyadenylation of the primary transcripts of a single gene locus at 1q31-q32.