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CYP11A1 Antibodies
AND CYP11A1 ELISA kits, CYP11A1 Proteins
Many biological assays use antibodies to detect CYP11A1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CYP11A1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CYP11A1 antibodies...
Designing a Western blot for CYP11A1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CYP11A1 Western Blot GuideCYP11A1 Infographic by Boster Bio
All CYP11A1 Products
Product
Figures
Specificity
Applications
Price
Anti-CYP11A1 Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, WB
$370
Cat # A01071-2
100 μg/vial
Cat # A01071-2
100 μg/vial
CYP11A1 Overview
Facts about Cholesterol side-chain cleavage enzyme, mitochondrial.
Cholesterol side-chain cleavage enzyme, mitochondrial (CYP11A1)
Catalyzes the side-chain cleavage reaction of cholesterol to pregnenolone, the precursor of most steroid hormones. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CYP11A1 |
| Uniprot: | P05108 |
| Entrez: | 1583 |
Family
| Belongs to: |
|---|
| cytochrome P450 family |
Alternative Names
Cholesterol desmolase; cholesterol monooxygenase (side-chain-cleaving); cholesterol side-chain cleavage enzyme, mitochondrial; CYPXIA1; Cytochrome P450 11A1; Cytochrome P450(scc); cytochrome P450, family 11, subfamily A, polypeptide 1; cytochrome P450C11A1; EC 1.14.15; EC 1.14.15.6; steroid 20-22-lyase; subfamily XIA (cholesterol side chain cleavage)
Molecular Weight
Mass (kDA):
60.102 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 15q24.1 |
| Sequence: | 15; NC_000015.10 (74337762..74367646, complement) |
Subcellular Localizations
Mitochondrion inner membrane; Peripheral membrane protein. Localizes to the matrix side of the mitochondrion inner membrane.
Diseases
- Malignant Neoplasms
- Neoplasms
- Polycystic Ovary Syndrome
- Adrenal Gland Hypofunction
- Hyperplasia
- Infertility
- Pituitary Diseases
- Hypertensive Disease
- Disorders Of Sex Development
- Prostatic Neoplasms
- Malignant Neoplasm Of Prostate
- Malignant Neoplasm Of Breast
Pathways
- Secretion
- Transport
- Luteinization
- Ovulation
- Cell Proliferation
- Localization
- Cholesterol Transport
- Progesterone Secretion
- Spermatogenesis
- Cell Differentiation
- Fertilization
- Cortisol Secretion
- Cell Cycle
PTMs
- Cleavage
- Phosphorylation
- Hydroxylation
- Reduction
Research Areas
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CYP11A1
bosterbio.com/bosterbio-gene-info-cards/CYP11A1
References
PMID: 3024157 by Chung B.-C., et al. Human cholesterol side-chain cleavage enzyme, P450scc: cDNA cloning, assignment of the gene to chromosome 15, and expression in the placenta.
PMID: 3038854 by Morohashi K., et al. Gene structure of human cytochrome P-450(SCC), cholesterol desmolase.
1 Publications of Boster CYP11A1 Antibodies & ELISA Kits
- PubMed ID: 23555723, Abnormal Apoptosis of Trophoblastic Cells Is Related to the Up-Regulation of CYP...
*More publications can be found for each product on its corresponding product page