Anti-CYP11A1 Antibody Picoband™

CYP11A1 antibody

Boster Bio Anti-CYP11A1 Antibody Picoband™ catalog # A01071-2. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A01071-2
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ELISA, WB

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Product Name

Anti-CYP11A1 Antibody Picoband™

View all CYP11A1 Antibodies

SKU/Catalog Number

A01071-2

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-CYP11A1 Antibody Picoband™ catalog # A01071-2. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Cite This Product

Anti-CYP11A1 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01071-2)

Host

Rabbit

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human CYP11A1 recombinant protein (Position: H72-Q461).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A01071-2 is reactive to CYP11A1 in Human, Mouse, Rat

Applications

A01071-2 is guaranteed for ELISA, WB Boster Guarantee

Observed Molecular Weight

50 kDa

Calculated molecular weight

60.102kDa

Background of CYP11A1

CYP11A1 (Cytochrome p450, family 11, subfamily A, polypeptide 1), commonly referred to as P450scc, is a mitochondrial enzyme associated with the conversion of cholesterol to pregnenolone. CYP11A1 is a member of the cytochrome P450 superfamily of enzymes. The CYP11A1 gene is mapped on 15q24.1. Expression of the CYP11A1 gene may play a role in skin physiology and pathology and that cutaneous proopiomelanocortin activity may be autoregulated by a feedback mechanism involving glucocorticoids synthesized locally. Using in vitro studies, CYP11A1 catalyzed the side-chain cleavage of 7-dehydrocholesterol to form 7-dehydropregnenolone. In addition, CYP11A1 catalyzed the metabolism of biologically inert vitamin D3, which is formed from 7-dehydrocholesterol, to form 2 hydroxylated products, 20-hydroxyvitamin D3 and 20, 22-dihydroxyvitamin D3. Mutations in the CYP11A1 gene cause congenital adrenal insufficiency with partial or complete 46, XY sex reversal.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
Direct ELISA, 0.1-0.5 μg/ml, Human

Validation Images & Assay Conditions

Gene/Protein Information For CYP11A1 (Source: Uniprot.org, NCBI)

Gene Name

CYP11A1

Full Name

Cholesterol side-chain cleavage enzyme, mitochondrial

Weight

60.102kDa

Superfamily

cytochrome P450 family

Alternative Names

Cholesterol desmolase; cholesterol monooxygenase (side-chain-cleaving); cholesterol side-chain cleavage enzyme, mitochondrial; CYPXIA1; Cytochrome P450 11A1; Cytochrome P450(scc); cytochrome P450, family 11, subfamily A, polypeptide 1; cytochrome P450C11A1; EC 1.14.15; EC 1.14.15.6; steroid 20-22-lyase; subfamily XIA (cholesterol side chain cleavage) CYP11A1 CYP11A, CYPXIA1, P450SCC cytochrome P450 family 11 subfamily A member 1 cholesterol side-chain cleavage enzyme, mitochondrial|cholesterol 20-22 desmolase|cholesterol monooxygenase (side-chain cleaving)|cytochrome P450 11A1|cytochrome P450 family 11 subfamily A polypeptide 1|cytochrome P450(scc)|cytochrome P450, subfamily XIA (cholesterol side chain cleavage)|steroid 20-22-lyase

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on CYP11A1, check out the CYP11A1 Infographic

CYP11A1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CYP11A1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A01071-2

100μg

$370
A01071-2-10ug

10μg sample (liquid)

$99
A01071-2-Biotin

100 μg Biotin conjugated

$570
A01071-2-Cy3

100 μg Cy3 conjugated

$570
A01071-2-Dylight488

100 μg Dylight488 conjugated

$570
A01071-2-Dylight550

100 μg Dylight550 conjugated

$570
A01071-2-Dylight594

100 μg Dylight594 conjugated

$570
A01071-2-FITC

100 μg FITC conjugated

$570
A01071-2-HRP

100 μg HRP conjugated

$570
A01071-2-APC

100 μg APC conjugated

$670
A01071-2-PE

100 μg PE conjugated

$670
A01071-2-carrier-free

Carrier Free

$370

More conjugates/formats

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A01071-2
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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