Anti-CYP11A1 Antibody

CYP11A1 antibody

Boster Bio Anti-CYP11A1 Antibody catalog # A01071. Tested in WB,ICC applications. This antibody reacts with Human,Mouse,Rat.

Product Info Summary

SKU: A01071
Size: 100ul
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ICC, WB

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Product Name

Anti-CYP11A1 Antibody

View all CYP11A1 Antibodies

SKU/Catalog Number

A01071

Size

100ul

Form

Liquid

Description

Boster Bio Anti-CYP11A1 Antibody catalog # A01071. Tested in WB,ICC applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-CYP11A1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01071)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human NOS1 around the phosphorylation site of S852.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A01071 is reactive to CYP11A1 in Human, Mouse, Rat

Applications

A01071 is guaranteed for ICC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

60.102kDa

Background of CYP11A1

Involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. May represent an important signaling intermediate between neuropeptide activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. Interacts with the SH2 domain of Grb2. May phosphorylate the voltage-gated potassium channel protein Kv1.2. Its activation is highly correlated with the stimulation of c-Jun N-terminal kinase activity. Involved in osmotic stress-dependent SNCA 'Tyr-125' phosphorylation.

Gluck SL, et al. (2004) J Clin Invest; 114(12): 1696-1699
Benzing T, et al. (2001) Proc Natl Acad Sci U S A; 98(17): 9784-9789
Tian D, et al. (2002) Mol Cell Biol; 22(8): 2650-2662
Lu Z, et al. (2001) Mol Cell Biol; 21(12): 4016-4031
Krishnan HH, et al. (2006) J Virol; 80(3): 1167-1180

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:1000
ICC: 1:50-1:200

Validation Images & Assay Conditions

Gene/Protein Information For CYP11A1 (Source: Uniprot.org, NCBI)

Gene Name

CYP11A1

Full Name

Cholesterol side-chain cleavage enzyme, mitochondrial

Weight

60.102kDa

Superfamily

cytochrome P450 family

Alternative Names

Cholesterol desmolase; cholesterol monooxygenase (side-chain-cleaving); cholesterol side-chain cleavage enzyme, mitochondrial; CYPXIA1; Cytochrome P450 11A1; Cytochrome P450(scc); cytochrome P450, family 11, subfamily A, polypeptide 1; cytochrome P450C11A1; EC 1.14.15; EC 1.14.15.6; steroid 20-22-lyase; subfamily XIA (cholesterol side chain cleavage) CYP11A1 CYP11A, CYPXIA1, P450SCC cytochrome P450 family 11 subfamily A member 1 cholesterol side-chain cleavage enzyme, mitochondrial|cholesterol 20-22 desmolase|cholesterol monooxygenase (side-chain cleaving)|cytochrome P450 11A1|cytochrome P450 family 11 subfamily A polypeptide 1|cytochrome P450(scc)|cytochrome P450, subfamily XIA (cholesterol side chain cleavage)|steroid 20-22-lyase

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on CYP11A1, check out the CYP11A1 Infographic

CYP11A1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for CYP11A1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A01071-100ul

100ul

$405

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*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
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