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- Table of Contents
Cytochrome P450 7A1 Antibodies
AND CYP7A1 ELISA kits, Cytochrome P450 7A1 Proteins
Many biological assays use antibodies to detect Cytochrome P450 7A1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cytochrome P450 7A1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cytochrome P450 7A1 antibodies...
Designing a Western blot for Cytochrome P450 7A1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CYP7A1 Western Blot GuideCYP7A1 Infographic by Boster Bio
All CYP7A1 Products
Product
Figures
Specificity
Applications
Price
Anti-CYP7A1 Antibody Picoband®
7 Citations
Human, Rat
Flow Cytometry, WB
$370
Cat # RP1079
100 μg/vial
Cat # RP1079
100 μg/vial
Anti-CYP7A1 Antibody Picoband®
1 Citations
Human
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01601
100 μg/vial
Cat # A01601
100 μg/vial
CYP7A1 Overview
Facts about Cytochrome P450 7A1.
Cytochrome P450 7A1 (CYP7A1)
Catalyzes a rate-limiting step in cholesterol catabolism and bile acid biosynthesis by introducing a hydrophilic moiety at position 7 of cholesterol. Significant for cholesterol homeostasis.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | CYP7A1 |
| Uniprot: | P22680 |
| Entrez: | 1581 |
Family
| Belongs to: |
|---|
| cytochrome P450 family |
Alternative Names
Cholesterol 7-alpha-hydroxylase; cholesterol 7-alpha-monooxygenase; CP7A; CYP7; CYP7A1; CYP7MGC126826; CYPVII; Cytochrome P450 7A1; cytochrome P450, family 7, subfamily A, polypeptide 1; cytochrome P450, subfamily VIIA (cholesterol 7 alpha-monooxygenase); cytochrome P450, subfamily VIIA polypeptide 1; EC 1.14.13; EC 1.14.13.17; MGC138389; polypeptide 1
Molecular Weight
Mass (kDA):
57.661 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 8q12.1 |
| Sequence: | 8; NC_000008.11 (58490178..58500163, complement) |
Tissue Specificity
Detected in liver.
Subcellular Localizations
Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein.
Diseases
- Hypercholesterolemia
- Cholestasis
- Liver Carcinoma
- Cholecystolithiasis
- Obesity
- Hyperlipidemia
- Atherosclerosis
- Diabetes Mellitus
- Liver Diseases
- Injury To Liver
- Fatty Liver
- Inflammation
- Insulin Resistance
Pathways
- Excretion
- Cholesterol Homeostasis
- Transport
- Secretion
- Cholesterol Transport
- Lipid Homeostasis
- Intestinal Cholesterol Absorption
- Gallstone Formation
- Reverse Cholesterol Transport
- Intestinal Absorption
- Pathogenesis
- Reverse Transcription
- Gluconeogenesis
PTMs
- Hydroxylation
- Phosphorylation
- Oxidation
- Acetylation
- Deacetylation
- Nitration
- Methylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CYP7A1
bosterbio.com/bosterbio-gene-info-cards/CYP7A1
References
PMID: 8439551 by Nishimoto M., et al. Structure of the gene encoding human liver cholesterol 7 alpha- hydroxylase.
PMID: 2384150 by Noshiro M., et al. Molecular cloning and sequence analysis of cDNA encoding human cholesterol 7 alpha-hydroxylase.
1 Publications of Boster Cytochrome P450 7A1 Antibodies & ELISA Kits
- PubMed ID: 10.1093/toxsci/kfv155, Cellular Accumulation and Toxic Effects of Bile Acids in Cyclosporine A-Treated ...
*More publications can be found for each product on its corresponding product page