Transcription factor E2F5 (E2F5)

Transcriptional activator that binds to E2F sites, these websites are found in the promoter of many genes whose products are involved in cell proliferation. May mediate growth factor- initiated signal transduction.

It's likely involved in the early responses of resting cells to growth factor stimulation. Specifically required for multiciliate cell differentiation: jointly with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis.