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- Table of Contents
Facts about Transcription factor E2F5.
It's likely involved in the early responses of resting cells to growth factor stimulation. Specifically required for multiciliate cell differentiation: jointly with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis.
Human | |
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Gene Name: | E2F5 |
Uniprot: | Q15329 |
Entrez: | 1875 |
Belongs to: |
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E2F/DP family |
E2F transcription factor 5, p130-binding; E2F-5; transcription factor E2F5
Mass (kDA):
37.61 kDA
Human | |
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Location: | 8q21.2 |
Sequence: | 8; NC_000008.11 (85177154..85214518) |
Nucleus.
PMID: 8589754 by Itoh A., et al. Structural characterization and specificity of expression of E2F-5: a new member of the E2F family of transcription factors.
PMID: 7760804 by Hijmans E.M., et al. E2F-5, a new E2F family member that interacts with p130 in vivo.