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- Table of Contents
Glutamate decarboxylase 2 Antibodies
AND GAD2 ELISA kits, Glutamate decarboxylase 2 Proteins
Many biological assays use antibodies to detect Glutamate decarboxylase 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Glutamate decarboxylase 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Glutamate decarboxylase 2 antibodies...
Designing a Western blot for Glutamate decarboxylase 2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the GAD2 Western Blot GuideGAD2 Infographic by Boster Bio
All GAD2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M03142
100 μg/vial
Cat # M03142
100 μg/vial
Human, Mouse, Rat
ELISA, IF, ICC, WB
$370
Cat # A03144-1
100 μg/vial
Cat # A03144-1
100 μg/vial
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M03142-2
100 μg
Cat # M03142-2
100 μg
GAD2 Overview
Facts about Glutamate decarboxylase 2.
Glutamate decarboxylase 2 (GAD2)
Catalyzes the production of GABA. .
Gene Information
| Human | |
|---|---|
| Gene Name: | GAD2 |
| Uniprot: | Q05329 |
| Entrez: | 2572 |
Family
| Belongs to: |
|---|
| group II decarboxylase family |
Alternative Names
EC 4.1.1; EC 4.1.1.15; GAD2; GAD65; GAD-65; GAD65MGC161605; glutamate decarboxylase 2 (pancreatic islets and brain, 65kD); glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa); glutamate decarboxylase 2; Glutamate decarboxylase 65 kDa isoform; Glutamate decarboxylase-2 (pancreas); MGC161607,65 kDa glutamic acid decarboxylase
Molecular Weight
Mass (kDA):
65.411 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 10p12.1 |
| Sequence: | 10; NC_000010.11 (26216307..26304562) |
Subcellular Localizations
Cytoplasm, cytosol. Cytoplasmic vesicle. Cell junction, synapse, presynaptic cell membrane; Lipid-anchor. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Associated to cytoplasmic vesicles. In neurons, cytosolic leaflet of Golgi membranes and presynaptic clusters.
Diseases
- Obesity
- Schizophrenia
- Diabetes Mellitus
- Diabetes Mellitus, Insulin-dependent
- Obesity, Morbid
- Anxiety Disorders
- Depressive Disorder
- Malignant Neoplasms
- Major Depressive Disorder
- Epilepsy
Interacting Proteins
- AGTRAP
- ARL6IP1
- CMTM5
- MAL2
- TMEM159
Pathways
- Pathogenesis
- Methylation
- Insulin Secretion
- Dna Methylation
- Secretion
- Transport
- Righting Reflex
- Sensory Processing
- Dna Hypermethylation
- Response To Hypoxia
- Synaptic Transmission
- Neuron Differentiation
- Ovulation
PTMs
- Methylation
Research Areas
- Diabetes Research
- Immune System Diseases
- Immunology
- Lipid and Metabolism
- Neuronal Cell Markers
- Neuroscience
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/GAD2
bosterbio.com/bosterbio-gene-info-cards/GAD2
References
PMID: 1924293 by Karlsen A.E., et al. Cloning and primary structure of a human islet isoform of glutamic acid decarboxylase from chromosome 10.
PMID: 1549570 by Bu D.-F., et al. Two human glutamate decarboxylases, 65-kDa GAD and 67-kDa GAD, are each encoded by a single gene.
4 Publications of Boster Glutamate decarboxylase 2 Antibodies & ELISA Kits
- PubMed ID: 10.1007/s00540-011-1199-z, Propofol protects against impairment of learning-memory and imbalance of hippoca...
- PubMed ID: 30068915, Gut microbe-derived metabolite trimethylamine N-oxide induces cardiac hypertroph...
- PubMed ID: 26199611, Acrylamide neurotoxicity on the cerebrum of weaning rats
- PubMed ID: 21444355, Shi J, Ma Y, Zheng M, Ruan Z, Liu J, Tian S, Zhang D, He X, Li G. Toxicol Ind He...
*More publications can be found for each product on its corresponding product page