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- Table of Contents
Histone deacetylase 1 Antibodies
AND HDAC1 ELISA kits, Histone deacetylase 1 Proteins
Many biological assays use antibodies to detect Histone deacetylase 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Histone deacetylase 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Histone deacetylase 1 antibodies...
Designing a Western blot for Histone deacetylase 1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the HDAC1 Western Blot GuideDesigning an IHC experiment for Histone deacetylase 1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the HDAC1 IHC GuideHDAC1 Infographic by Boster Bio
All HDAC1 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA, Flow Cytometry, IF, IHC, WB
$370
Cat # A05223-3
100 μg/vial
Cat # A05223-3
100 μg/vial
Anti-FKBP10 Antibody Picoband®
1 Citations
Human
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A05217-1
100 μg/vial
Cat # A05217-1
100 μg/vial
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M00256-2
20μL, 40μL, 100μL, 200μL
Cat # M00256-2
20μL, 40μL, 100μL, 200μL
Human, Mouse, Rat
ELISA
$540
Cat # EKC2197
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2197
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1260
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1260
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1261
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1261
1 kit, containing one 96-well plate and all necessary reagents
HDAC1 Overview
Facts about Histone deacetylase 1.
Histone deacetylase 1 (HDAC1)
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and modulates their function.
Gene Information
| Human | |
|---|---|
| Gene Name: | HDAC1 |
| Uniprot: | Q13547 |
| Entrez: | 3065 |
Family
| Belongs to: |
|---|
| histone deacetylase family |
Alternative Names
EC 3.5.1.98; GON-10; HD1; HD1DKFZp686H12203; Histone Deacetylase 1; KDAC1; reduced potassium dependency, yeast homolog-like 1; RPD3L1; RPD3L1RPD3
Molecular Weight
Mass (kDA):
55.103 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p35.2-p35.1 |
| Sequence: | 1; NC_000001.11 (32292083..32333628) |
Tissue Specificity
Ubiquitous, with higher levels in heart, pancreas and testis, and lower levels in kidney and brain.
Subcellular Localizations
Nucleus.
Diseases
- Malignant Neoplasms
- Neoplasms
- Traditional Serrated Adenoma
- Carcinoma
- Leukemia
- Malignant Neoplasm Of Breast
- Retinoblastoma
- Mammary Neoplasms
- Cell Transformation, Neoplastic
- Malignant Paraganglionic Neoplasm
- Neoplasm Metastasis
- Malignant Neoplasm Of Prostate
Pathways
- Cell Cycle
- Histone Acetylation
- Methylation
- Chromatin Remodeling
- Cell Proliferation
- Histone Deacetylation
- Cell Growth
- Dna Methylation
- Localization
- Cell Death
- Cell Cycle Arrest
- Cell Differentiation
- Gene Silencing
PTMs
- Acetylation
- Deacetylation
- Methylation
- Phosphorylation
- Demethylation
- Cleavage
- Ubiquitination
- Sumoylation
Research Areas
- Apoptosis
- Breast Cancer
- Cancer
- Cell Cycle and Replication
- Checkpoint signaling
- Chromatin Research
- Core ESC-Like Genes
- Epigenetics
- Loading Controls
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HDAC1
bosterbio.com/bosterbio-gene-info-cards/HDAC1
References
PMID: 8602529 by Taunton J., et al. A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p.
PMID: 8646880 by Furukawa Y., et al. Isolation and mapping of a human gene (RPD3L1) that is homologous to RPD3, a transcription factor in Saccharomyces cerevisiae.