Vigilin Antibodies

AND HDLBP ELISA kits, Vigilin Proteins

Many biological assays use antibodies to detect Vigilin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Vigilin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Vigilin antibodies...

We validate the specificity of these antibodies to Vigilin by testing them on tissues known to express HDLBP positively and negatively. Browse below to find the HDLBP antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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HDLBP Infographic by Boster Bio

All HDLBP Products

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Specificity

Applications

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Anti-Vigilin HDLBP Antibody

Western blot analysis of extracts of various cell lines, using HDLBP antibody at 1:3000 dilution

Immunohistochemistry of paraffin-embedded rat liver using HDLBP antibody at dilution of 1:100

Immunohistochemistry of paraffin-embedded human liver using HDLBP antibody at dilution of 1:100

Human, Mouse, Rat

IF, IHC, ICC, WB

$405
Cat # A06727
100ul

Anti-HDLBP Rabbit Monoclonal Antibody

Western blot analysis of HDLBP expression in HeLa cell lysate

Human, Mouse, Rat

IHC, WB

$370
Cat # M06727
100 μl/vial

Anti-HDLBP Rabbit Monoclonal Antibody

Western blot analysis of HDLBP expression in Jurkat cell lysate

Human

$370
Cat # M06727-1
100 μl/vial

HDLBP (NM_005336) Human Over-expression Lysate

Human

$628
Cat # LS003069
20 µg, 100 µg

Anti-HDLBP Antibody Picoband®

Western blot analysis of HDLBP using anti-HDLBP antibody (A06727-2)

IF analysis of HDLBP using anti-HDLBP antibody (A06727-2)

Flow Cytometry analysis of 293T cells using anti-HDLBP antibody (A06727-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A06727-2
100 µg/vial

HDLBP Overview

Facts about Vigilin.

HDLBP 3D structure. Source: alphafold

Vigilin (HDLBP)

Appears to play a role in cell sterol metabolism. It may function to protect cells from over-accumulation of cholesterol.

Gene Information

Human
Gene Name:	HDLBP
Uniprot:	Q00341
Entrez:	3069

Family

Belongs to:

No superfamily

Alternative Names

HBPFLJ16432; HDL-binding protein; high density lipoprotein binding protein; High density lipoprotein-binding protein; PRO2900; VGLvigilin

Molecular Weight

Mass (kDA):
141.456 kDA

Genomic Context


Human

Location:	2q37.3
Sequence:	2; NC_000002.12 (241227264..241315842, complement)

Subcellular Localizations

Cytoplasm. Nucleus.

Diseases

Haploinsufficiency
Dyslipidemias
Autistic Disorder
Malignant Neoplasms
Graves Disease
Steatohepatitis
Malignant Neoplasm Of Breast
Brachydactyly-mental Retardation Syndrome
Mammary Neoplasms

Fatty Liver, Alcoholic
Lipid Metabolism Disorders
Steatosis

Interacting Proteins

CTCF

Pathways

Transport
Reverse Transcription
Translation
Sterol Transport
Fertilization
Cholesterol Transport

Localization

PTMs

Carboxylation

Research Areas

Cholesterol Metabolism
Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HDLBP

References

PMID: 1318310 by McKnight G.L., et al. Cloning and expression of a cellular high density lipoprotein-binding protein that is up-regulated by cholesterol loading of cells.

PMID: 8605996 by Kugler S., et al. Vigilin contains a functional nuclear localisation sequence and is present in both the cytoplasm and the nucleus.