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Histone deacetylase 5 Antibodies
AND HDAC5 ELISA kits, Histone deacetylase 5 Proteins
Many biological assays use antibodies to detect Histone deacetylase 5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Histone deacetylase 5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Histone deacetylase 5 antibodies...
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HDAC5 Infographic by Boster Bio
All HDAC5 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
WB
$370
Cat # PA2180
100 μg/vial
Cat # PA2180
100 μg/vial
Human, Mouse
ELISA
$480
Cat # EKC1265
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1265
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse
ELISA
$540
Cat # EKC2039
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2039
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse
ELISA
$540
Cat # EKC2424
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2424
1 kit, containing two 96-well plates and all necessary reagents
Anti-HDAC5 Antibody Picoband®
1 Citations 1 Q&As
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01230-6
100 μg/vial
Cat # A01230-6
100 μg/vial
HDAC5 Overview
Facts about Histone deacetylase 5.
Histone deacetylase 5 (HDAC5)
Responsible for the deacetylation of lysine residues on the N-terminal portion of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays a significant role in transcriptional regulation, cell cycle progression and developmental events.
Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C.
Gene Information
| Human | |
|---|---|
| Gene Name: | HDAC5 |
| Uniprot: | Q9UQL6 |
| Entrez: | 10014 |
Family
| Belongs to: |
|---|
| histone deacetylase family |
Alternative Names
Antigen NY-CO-9; EC 3.5.1.98; FLJ90614; HD5; histone deacetylase 5; KIAA0600; NY-CO-9
Molecular Weight
Mass (kDA):
121.978 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17q21.31 |
| Sequence: | 17; NC_000017.11 (44076753..44123651, complement) |
Tissue Specificity
Ubiquitous.
Subcellular Localizations
Nucleus. Cytoplasm. Shuttles between the nucleus and the cytoplasm. In muscle cells, it shuttles into the cytoplasm during myocyte differentiation. The export to cytoplasm depends on the interaction with a 14-3-3 chaperone protein and is due to its phosphorylation at Ser-259 and Ser-498 by AMPK, CaMK1 and SIK1.
Diseases
- Hypertrophy
- Cardiac Hypertrophy
- Heart Failure
- Malignant Neoplasms
- Neoplasms
- Traditional Serrated Adenoma
- Inflammation
- Cardiomyopathies
- Malignant Paraganglionic Neoplasm
- Hypertensive Disease
- Carcinoma
- Heart Diseases
- Depressive Disorder
Interacting Proteins
- BRMS1
- GATA3
- Grk5
- RUNX3
- SFN
- YWHAZ
Pathways
- Nuclear Export
- Localization
- Histone Acetylation
- Cell Differentiation
- Histone Deacetylation
- Nuclear Import
- Cell Proliferation
- Pathogenesis
- Rna Interference
- Regeneration
- Methylation
- Cell Death
- Cell Growth
PTMs
- Phosphorylation
- Acetylation
- Deacetylation
- Methylation
- Dephosphorylation
Research Areas
- Breast Cancer
- Cancer
- Cell Cycle and Replication
- Chromatin Research
- Epigenetics
- Phospho-Specific
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HDAC5
bosterbio.com/bosterbio-gene-info-cards/HDAC5
References
PMID: 10220385 by Grozinger C.M., et al. Three proteins define a class of human histone deacetylases related to yeast Hda1p.
PMID: 9610721 by Scanlan M.J., et al. Characterization of human colon cancer antigens recognized by autologous antibodies.