IDO2 Antibodies

AND IDO2 ELISA kits, IDO2 Proteins

Many biological assays use antibodies to detect IDO2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IDO2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IDO2 antibodies...

We validate the specificity of these antibodies to IDO2 by testing them on tissues known to express IDO2 positively and negatively. Browse below to find the IDO2 antibody that suites your experiment. We have 9 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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IDO2 Infographic by Boster Bio

All IDO2 Products

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Product

Figures

Specificity

Applications

Price

Anti-INDOL1/IDO2 Antibody Picoband®

2 Q&As

Western blot analysis of IDO2 using anti-IDO2 antibody (PA1612)

Human

$370
Cat # PA1612
100 μg/vial

Anti-IDO2 Monoclonal Antibody

5 Q&As

Mouse

ELISA, IF, WB

$658
Cat # M06002
100ug

Anti-Indoleamine 2,3-dioxygenase 2 IDO2 Antibody

Western blot (WB) analysis of IDO2 polyclonal antibody at 1:500 dilution
Lane1:HEK293T whole cell lysate
Lane2:Raw264

Human, Mouse, Rat

$405
Cat # A06002-1
100ul

Anti-IDO-2/IDO2 Antibody Picoband®

1 Citations

Western blot analysis of IDO-2/IDO2 using anti-IDO-2/IDO2 antibody (A06002-2)

Flow Cytometry analysis of K562 cells using anti-IDO-2/IDO2 antibody (A06002-2)

IHC analysis of IDO-2/IDO2 using anti-IDO-2/IDO2 antibody (A06002-2)

Human, Monkey, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A06002-2
100 μg/vial

Anti-INDOL1 (IDO2) Mouse Monoclonal Antibody [Clone ID: OTI1A4]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IDO2 (Right lane) cDNA for 48 hrs and lysed

HEK293T cells transfected with either IDO2 (Myc-DDK-tagged) overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-IDO2 antibody (M06002-1)

Flow cytometric Analysis of Jurkat cells

Human

Flow Cytometry, WB

$523
Cat # M06002-1
100 µl

Anti-INDOL1 (IDO2) Mouse Monoclonal Antibody [Clone ID: OTI2B9]

Western blot analysis of IDO2 using anti-IDO2 antibody (M06002-2)

Immunofluorescent staining of HeLa cells using anti-IDO2 mouse monoclonal antibody (M06002-2)

Human

IF, WB

$523
Cat # M06002-2
100 µl

Anti-INDOL1 (IDO2) Mouse Monoclonal Antibody [Clone ID: OTI11B2]

Human

IHC, WB

$523
Cat # M06002-3
100 µl

INDOL1 (IDO2) (NM_194294) Human Over-expression Lysate

Human

$960
Cat # LS169355
20 µg, 100 µg

Anti-IDO2 Reference Antibody (LIMR patent anti-IDO2)

The purity of Anti-IDO2 Reference Antibody (LIMR patent anti-IDO2)is more than 97

Human, Mouse

ELISA, Flow Cytometry, Functional Assay, Kinetics

$486
Cat # M06002-4
100 μg

IDO2 Overview

Facts about Indoleamine 2,3-dioxygenase 2.

IDO2 3D structure. Source: alphafold

Indoleamine 2,3-dioxygenase 2 (IDO2)

Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway (PubMed:17671174). Involved in immune regulation.

May not play a substantial role in tryptophan-related tumoral immunity (PubMed:25691885). .

Gene Information

Human
Gene Name:	IDO2
Uniprot:	Q6ZQW0
Entrez:	169355

Family

Belongs to:

indoleamine 2,3-dioxygenase family

Alternative Names

EC 1.13.11.-; IDO2; Ido-2; INDOL1; INDOL1indoleamine-pyrrole 2,3 dioxygenase-like 1; indoleamine 2,3-dioxygenase 2; Indoleamine 2,3-dioxygenase-2; indoleamine 2,3-dioxygenase-like 1 protein; Indoleamine 2,3-dioxygenase-like protein 1; Indoleamine-pyrrole 2,3-dioxygenase-like protein 1

Molecular Weight

Mass (kDA):
47.075 kDA

Genomic Context


Human

Location:	8p11.21
Sequence:	8; NC_000008.11 (39934955..40016391)

Tissue Specificity

Detected in liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, and colon (PubMed:17671174). Also expressed at low level in testis and thyroid. Not expressed in the majority of human tumor samples (>99%) (PubMed:25691885).

Diseases

Malignant Neoplasms
Neoplasms
Decreased Immunologic Activity [pe]
Depressive Disorder
Inflammation
Carcinoma
Renal Cell Carcinoma
Malignant Paraganglionic Neoplasm
Autoimmune Diseases
Malignant Neoplasm Of Pancreas
Cell Transformation, Neoplastic
Autoimmune Reaction

Neoplasm Metastasis
Melanoma
Pulmonary Embolism
Malignant Tumor Of Colon
Kidney Neoplasm
Lung Diseases
Lung Diseases, Obstructive

Pathways

Cell Proliferation
Translation
Cell Activation
T Cell Activation
Immune Response
Localization
Senescence
Stem Cell Proliferation
Cellular Localization
T Cell Proliferation

Cell Growth
T Cell Anergy
Angiogenesis
Pathogenesis
Secretion

PTMs

Phosphorylation

Cleavage

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IDO2

References

PMID: 17499941 by Ball H.J., et al. Characterization of an indoleamine 2,3-dioxygenase-like protein found in humans and mice.

PMID: 17671174 by Metz R., et al. Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan.