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- Table of Contents
IDO2 Antibodies
AND IDO2 ELISA kits, IDO2 Proteins
Many biological assays use antibodies to detect IDO2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with IDO2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop IDO2 antibodies...
Designing a Western blot for IDO2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the IDO2 Western Blot GuideIDO2 Infographic by Boster Bio
All IDO2 Products
Product
Figures
Specificity
Applications
Price
Anti-IDO-2/IDO2 Antibody Picoband®
1 Citations
Human, Monkey, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A06002-2
100 μg/vial
Cat # A06002-2
100 μg/vial
Human
IF, WB
$523
Cat # M06002-2
100 µl
Cat # M06002-2
100 µl
Human
IHC, WB
$523
Cat # M06002-3
100 µl
Cat # M06002-3
100 µl
Human
Flow Cytometry, WB
$523
Cat # M06002-1
100 µl
Cat # M06002-1
100 µl
Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M06002-4
100 μg
Cat # M06002-4
100 μg
IDO2 Overview
Facts about Indoleamine 2,3-dioxygenase 2.
Indoleamine 2,3-dioxygenase 2 (IDO2)
Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway (PubMed:17671174). Involved in immune regulation.
May not play a substantial role in tryptophan-related tumoral immunity (PubMed:25691885). .
Gene Information
| Human | |
|---|---|
| Gene Name: | IDO2 |
| Uniprot: | Q6ZQW0 |
| Entrez: | 169355 |
Family
| Belongs to: |
|---|
| indoleamine 2,3-dioxygenase family |
Alternative Names
EC 1.13.11.-; IDO2; Ido-2; INDOL1; INDOL1indoleamine-pyrrole 2,3 dioxygenase-like 1; indoleamine 2,3-dioxygenase 2; Indoleamine 2,3-dioxygenase-2; indoleamine 2,3-dioxygenase-like 1 protein; Indoleamine 2,3-dioxygenase-like protein 1; Indoleamine-pyrrole 2,3-dioxygenase-like protein 1
Molecular Weight
Mass (kDA):
47.075 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 8p11.21 |
| Sequence: | 8; NC_000008.11 (39934955..40016391) |
Tissue Specificity
Detected in liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, and colon (PubMed:17671174). Also expressed at low level in testis and thyroid. Not expressed in the majority of human tumor samples (>99%) (PubMed:25691885).
Diseases
- Malignant Neoplasms
- Neoplasms
- Decreased Immunologic Activity [pe]
- Depressive Disorder
- Inflammation
- Carcinoma
- Renal Cell Carcinoma
- Malignant Paraganglionic Neoplasm
- Autoimmune Diseases
- Malignant Neoplasm Of Pancreas
- Cell Transformation, Neoplastic
- Autoimmune Reaction
Pathways
- Cell Proliferation
- Translation
- Cell Activation
- T Cell Activation
- Immune Response
- Localization
- Senescence
- Stem Cell Proliferation
- Cellular Localization
- T Cell Proliferation
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/IDO2
bosterbio.com/bosterbio-gene-info-cards/IDO2
References
PMID: 17499941 by Ball H.J., et al. Characterization of an indoleamine 2,3-dioxygenase-like protein found in humans and mice.
PMID: 17671174 by Metz R., et al. Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan.