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- Table of Contents
7 Citations 13 Q&As
13 Citations 13 Q&As
Facts about Lipopolysaccharide-binding protein.
Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide (PubMed:7517398, PubMed:24120359).
| Human | |
|---|---|
| Gene Name: | LBP |
| Uniprot: | P18428 |
| Entrez: | 3929 |

| Belongs to: |
|---|
| BPI/LBP/Plunc superfamily |

LBP; lipopolysaccharide binding protein; lipopolysaccharide-binding protein; LPS-binding protein; MGC22233
Mass (kDA):
53.384 kDA

| Human | |
|---|---|
| Location: | 20q11.23 |
| Sequence: | 20; NC_000020.11 (38346482..38377013) |
Detected in blood serum (at protein level).
Secreted. Cytoplasmic granule membrane. Membrane-associated in polymorphonuclear Leukocytes (PMN) granules.





PMID: 2402637 by Schumann R.R., et al. Structure and function of lipopolysaccharide binding protein.
PMID: 7517398 by Wilde C.G., et al. Bactericidal/permeability-increasing protein and lipopolysaccharide (LPS)-binding protein. LPS binding properties and effects on LPS- mediated cell activation.
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