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- Table of Contents
LBP Antibodies
AND LBP ELISA kits, LBP Proteins
Many biological assays use antibodies to detect LBP, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LBP in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LBP antibodies...
Designing a Western blot for LBP? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the LBP Western Blot GuideLBP Infographic by Boster Bio
All LBP Products
Product
Figures
Specificity
Applications
Price
Human LBP ELISA Kit PicoKine®
7 Citations
Human
ELISA
$450
Cat # EK1271
96 wells/kit, with removable strips.
Cat # EK1271
96 wells/kit, with removable strips.
Mouse LBP ELISA Kit PicoKine®
13 Citations
Mouse
ELISA
$450
Cat # EK1274
96 wells/kit, with removable strips.
Cat # EK1274
96 wells/kit, with removable strips.
Human
Flow Cytometry, IF, IHC, IHC-F, ICC, WB
$370
Cat # PB10094
100 μg/vial
Cat # PB10094
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M01691
100 μl
Cat # M01691
100 μl
Human, Mouse
ELISA, IF, IHC-P, WB
$481
Cat # A01691
0.1 mg
Cat # A01691
0.1 mg
LBP Overview
Facts about Lipopolysaccharide-binding protein.
Lipopolysaccharide-binding protein (LBP)
Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of Gram-negative germs (PubMed:7517398, PubMed:24120359).
Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide (PubMed:7517398, PubMed:24120359).
Gene Information
| Human | |
|---|---|
| Gene Name: | LBP |
| Uniprot: | P18428 |
| Entrez: | 3929 |
Family
| Belongs to: |
|---|
| BPI/LBP/Plunc superfamily |
Alternative Names
LBP; lipopolysaccharide binding protein; lipopolysaccharide-binding protein; LPS-binding protein; MGC22233
Molecular Weight
Mass (kDA):
53.384 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 20q11.23 |
| Sequence: | 20; NC_000020.11 (38346482..38377013) |
Tissue Specificity
Detected in blood serum (at protein level).
Subcellular Localizations
Secreted. Cytoplasmic granule membrane. Membrane-associated in polymorphonuclear Leukocytes (PMN) granules.
Diseases
- Pain
- Low Back Pain
- Back Pain
- Inflammation
- Systemic Infection
- Infective Disorder
- Flexed Fetal Attitude
- Inflammatory Response
- Bacterial Infections
- Septic Shock
- Chronic Pain
- Innate Immune Response
Interacting Proteins
- PRDX4
Pathways
- Immune Response
- Inflammatory Response
- Secretion
- Cell Activation
- Pathogenesis
- Cytokine Production
- Innate Immune Response
- Transport
- Localization
- Translation
- Macrophage Activation
- Phagocytosis
- Acute-phase Response
PTMs
- Phosphorylation
- Cleavage
- Oxidation
- Glycosylation
- Nitration
- Biotinylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LBP
bosterbio.com/bosterbio-gene-info-cards/LBP
References
PMID: 2402637 by Schumann R.R., et al. Structure and function of lipopolysaccharide binding protein.
PMID: 7517398 by Wilde C.G., et al. Bactericidal/permeability-increasing protein and lipopolysaccharide (LPS)-binding protein. LPS binding properties and effects on LPS- mediated cell activation.
15 Publications of Boster LBP Antibodies & ELISA Kits
- PubMed ID: 10.3390/nu11123004, The Effect of Hops (Humulus lupulus L.) Extract Supplementation on Weight Gain, ...
- PubMed ID: 10.3390/microorganisms7030076, Changes in Mouse Gut Microbial Community in Response to the Different Types of C...
- PubMed ID: 10.1038/srep22875, Reduction Impairs the Antibacterial Activity but Benefits the LPS Neutralization...
- PubMed ID: 10.1038/s41467-021-21472-1, Fecal microbiota transplantation in HIV: A pilot placebo-controlled study
- PubMed ID: 10.1038/s41419-021-04293-4, Gut-derived lipopolysaccharide remodels tumoral microenvironment and synergizes ...
- PubMed ID: 10.1016/j.jff.2019.103688, Prebiotic role of softwood hemicellulose in healthy mice model
- PubMed ID: 10.1016/j.foodres.2021.110456, Effect of Antarctic Krill Phospholipid (KOPL) on High Fat Diet-Induced Obesity i...
- PubMed ID: 10.1016/j.bbi.2019.09.001, Modulation of high fat diet-induced microbiome changes, but not behaviour, by mi...
- PubMed ID: 10.1002/cmdc.201900282, Roles of the Conserved Amino Acid Residues in Reduced Human Defensin 5: Cystei...
- PubMed ID: -, Xingwei Xiang,Xiaoling Zhou,Wenjie Wang,Yufang Zhou,Xuxia Zhou,Shanggui Deng,Bin...
- PubMed ID: 33890206, Dorigatti JD,Thyne KM,Ginsburg BC,Salmon AB.Beta-guanidinopropionic acid has age...
- PubMed ID: -, Xiaoling Zhou,Xingwei Xiang,Yufang Zhou,Tianyi Zhou,Shanggui Deng,Bin Zheng,Ping...
- PubMed ID: 33602945, Serrano-Villar S,Talavera-Rodríguez A,Gosalbes MJ,Madrid N,Pérez-Molina JA,Ell...
- PubMed ID: 33245424, Shi W, Bian L, Lv D, Bi S, Dai Y, Yang K, Lu H, Zhou H, Que Y, Wang D, Zhang Z, ...
- PubMed ID: 26960718, Reduction Impairs the Antibacterial Activity but Benefits the LPS Neutralization...
*More publications can be found for each product on its corresponding product page