This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Prokineticin-1 Antibodies
AND PROK1 ELISA kits, Prokineticin-1 Proteins
Many biological assays use antibodies to detect Prokineticin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Prokineticin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Prokineticin-1 antibodies...
Previous: Septin9
Next: CARD11
PROK1 Infographic by Boster Bio
All PROK1 Products
Product
Figures
Specificity
Applications
Price
Human EG-VEGF/PK1/PROK1 ELISA Kit PicoKine®
4 Citations 6 Q&As
Human
ELISA
$499
Cat # EK0575
96 wells/kit, with removable strips.
Cat # EK0575
96 wells/kit, with removable strips.
Human
$628
Cat # LS084432
20 µg, 100 µg
Cat # LS084432
20 µg, 100 µg
PROK1 Overview
Facts about Prokineticin-1.
Prokineticin-1 (PROK1)
Induces proliferation, migration and fenestration (the formation of tissue discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types.
Induces proliferation and differentiation, but not migration, of enteric neural crest cells. Directly influences neuroblastoma development by promoting the proliferation and migration of neuroblastoma cells.
Gene Information
| Human | |
|---|---|
| Gene Name: | PROK1 |
| Uniprot: | P58294 |
| Entrez: | 84432 |
Family
| Belongs to: |
|---|
| AVIT (prokineticin) family |
Alternative Names
EGVEGF; EG-VEGF; EGVEGFblack mamba toxin-related protein; Endocrine-gland-derived vascular endothelial growth factor; Mambakine; PK1mambakine; PRK1prokineticin-1; PROK1; Prokineticin 1
Molecular Weight
Mass (kDA):
11.715 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p13.3 |
| Sequence: | 1; NC_000001.11 (110451149..110457358) |
Tissue Specificity
Localizes to glandular epithelium, stroma and vascular epithelial cells of first trimester decidua (at protein level). Up-regulated in first trimester decidua when compared with non-pregnant endometrium. Expressed in the steroidogenic glands, ovary, testis, adrenal and placenta.
Subcellular Localizations
Secreted.
Diseases
- Tumor Angiogenesis
- Endometrial Polyp
- Neoplasms
- Malignant Neoplasms
- Pathologic Neovascularization
- Mycoplasma Pneumonia
- Hypoxia
- Carcinoma
- Ectopic Pregnancy
- Pancreatic Neoplasm
- Tissue Adhesions
- Endometriosis, Site Unspecified
Pathways
- Angiogenesis
- Secretion
- Localization
- Regulation Of Angiogenesis
- Decidualization
- Transport
- Cell Adhesion
- Muscle Contraction
- Inflammatory Response
- Monocyte Activation
- Cell Proliferation
- Smooth Muscle Contraction
- Parturition
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PROK1
bosterbio.com/bosterbio-gene-info-cards/PROK1
References
PMID: 11259612 by Li M., et al. Identification of two prokineticin cDNAs: recombinant proteins potently contract gastrointestinal smooth muscle.
PMID: 11528470 by LeCouter J., et al. Identification of an angiogenic mitogen selective for endocrine gland endothelium.
6 Publications of Boster Prokineticin-1 Antibodies & ELISA Kits
- PubMed ID: 10.1167/iovs.14-14734, Knockout of αA-Crystallin Inhibits Ocular Neovascularization
- PubMed ID: 10.1080/14767058.2017.1351536, Use of prokineticin-1 (PROK1), pregnancy-associated plasma protein A (PAPP-A) an...
- PubMed ID: 10.1016/j.placenta.2017.12.015, Relationship between second-trimester amniotic fluid levels of Prokineticin-1 an...
- PubMed ID: -, Efficacy of EP chemotherapy followed by IP chemotherapy combined with radiothera...
- PubMed ID: 28675948, Use of prokineticin-1 (PROK1), pregnancy-associated plasma protein A (PAPP-A) an...
- PubMed ID: 21139695, Administration of pigment epithelium-derived factor delivered by adeno-associate...
*More publications can be found for each product on its corresponding product page