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Product Info Summary
| SKU: | M00026-7 |
|---|---|
| Size: | 100 μg/vial |
| Reactive Species: | Human |
| Host: | Mouse |
| Application: | IHC, ICC, WB |
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Product info
Product Name
Anti-c-Myc Antibody (Monoclonal, 35M73)
SKU/Catalog Number
M00026-7
Size
100 μg/vial
Form
Lyophilized
Description
Boster Bio Anti-c-Myc Antibody (Monoclonal, 35M73) catalog # M00026-7. Tested in IHC, ICC, WB applications. This antibody reacts with Human.
Storage & Handling
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-c-Myc Antibody (Monoclonal, 35M73) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00026-7)
Host
Mouse
Contents
Mouse IgG in stabilizing components, 1.2% sodium acetate and 0.01mg NaN3.
Clonality
Monoclonal
Clone Number
35M73
Isotype
Mouse IgG1
Immunogen
Synthetic peptide corresponding to residues 408-439 of the human p62c-Myc protein.
Cross-reactivity
No cross-reactivity with other proteins
Reactive Species
M00026-7 is reactive to Myc in Human
Calculated molecular weight
48.9 kDa
Background of Myc
C-Myc is an oncogene that functions both in the stimulation of cell proliferation and in apoptosis. c-Myc elicits its oncogenic activity by causing immortalization, and to a lesser extent the transformation of cells, in addition to several other mechanisms. The c-MYC proto-oncogene encodes a transcription factor that is critical for cell growth and proliferation. It is one of the genes frequently altered in cancer cells in which it exhibits constitutive activity. Downregulation of c-Myc is critical for 2-Methoxyestradiol (2ME2)-induced oxidative stress and apoptosis in AML cells. And its up-regulation is important for promoting lymphocyte cell division, and demonstrating that GFP-c-Myc expression is a marker of proliferating lymphocytes in vivo.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M00026-7 is guaranteed for IHC, ICC, WB Boster Guarantee
Recommend Dilution
| Application | Dilution | Species |
|---|---|---|
| Western blot | 1μg/ml | Human |
| Immunohistochemistry (Paraffin-embedded Section) | 5μg/ml | Human |
| Immunocytochemistry | 1μg/ml | Human |
Validation Images & Assay Conditions
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Specific Publications For Anti-c-Myc Antibody (Monoclonal, 35M73) (M00026-7)
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