Anti-AMACR Antibody Picoband™

alpha-Methylacyl-CoA Racemase/AMACR antibody

Boster Bio Anti-AMACR Antibody Picoband™ catalog # PB9983. Tested in WB applications. This antibody reacts with Human, Rat. Cited in 1 publication(s).

Product Info Summary

SKU: PB9983
Size: 100 μg/vial
Reactive Species: Human, Rat
Host: Rabbit
Application: WB

Product Name

Anti-AMACR Antibody Picoband™

View all alpha-Methylacyl-CoA Racemase/AMACR Antibodies

SKU/Catalog Number

PB9983

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-AMACR Antibody Picoband™ catalog # PB9983. Tested in WB applications. This antibody reacts with Human, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-AMACR Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9983)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human AMACR, different from the related mouse and rat sequences by four amino acids.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

PB9983 is reactive to Amacr in Human, Rat

Applications

PB9983 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

42 kDa

Calculated molecular weight

41.704kDa

Background of alpha-Methylacyl-CoA Racemase/AMACR

Alpha-methylacyl-CoA racemase (AMACR) is a mitochondrial and peroxisomal enzyme. It encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml, Human, Rat

Validation Images & Assay Conditions

Gene/Protein Information For Amacr (Source: Uniprot.org, NCBI)

Gene Name

Amacr

Full Name

Alpha-methylacyl-CoA racemase

Weight

41.704kDa

Superfamily

CoA-transferase III family

Alternative Names

2-methylacyl-CoA racemase; alpha-Methylacyl-CoA Racemase; alphaMethylacylCoARacemase; AMACR; AMACRD; CBAS4; EC 5.1.99.4; RACE; RM Amacr|Mac, Macr1|alpha-methylacyl-CoA racemase|alpha-methylacyl-CoA racemase|2-arylpropionyl-CoA epimerase|2-methylacyl-CoA racemase|alpha-methylacyl-Coenzyme A racemase

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on Amacr, check out the Amacr Infographic

Amacr infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for Amacr: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

PB9983 has been cited in 1 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

A metanephric adenoma of the kidney associated with polycythemia: A case report

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5 Customer Q&As for Anti-AMACR Antibody Picoband™

Question

We are currently using anti-AMACR antibody PB9983 for rat tissue, and we are content with the WB results. The species of reactivity given in the datasheet says human, rat. Is it likely that the antibody can work on feline tissues as well?

Verified Customer

Verified customer

Asked: 2020-04-21

Answer

The anti-AMACR antibody (PB9983) has not been tested for cross reactivity specifically with feline tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in feline you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2020-04-21

Question

See attached the WB image, lot number and protocol we used for kidney using anti-AMACR antibody PB9983. Please let me know if you require anything else.

Verified Customer

Verified customer

Asked: 2019-12-20

Answer

Thank you very much for the data. Our lab team are working to resolve this as quickly as possible, and we appreciate your patience and understanding! You have provided everything we needed. Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2019-12-20

Question

I was wanting to use your anti-AMACR antibody for WB for human kidney on frozen tissues, but I want to know if it has been tested for this particular application. Has this antibody been tested and is this antibody a good choice for human kidney identification?

Verified Customer

Verified customer

Asked: 2018-05-15

Answer

It shows on the product datasheet, PB9983 anti-AMACR antibody has been tested for WB on human, rat tissues. We have an innovator award program that if you test this antibody and show it works in human kidney in IHC-frozen, you can get your next antibody for free.

Boster Scientific Support

Answered: 2018-05-15

Question

I was wanting to use to test anti-AMACR antibody PB9983 on human kidney for research purposes, then I may be interested in using anti-AMACR antibody PB9983 for diagnostic purposes as well. Is the antibody suitable for diagnostic purposes?

A. Anderson

Verified customer

Asked: 2015-05-28

Answer

The products we sell, including anti-AMACR antibody PB9983, are only intended for research use. They would not be suitable for use in diagnostic work. If you have the means to develop a product into diagnostic use, and are interested in collaborating with us and develop our product into an IVD product, please contact us for more discussions.

Boster Scientific Support

Answered: 2015-05-28

Question

Thank you for helping with my inquiry over the phone. Here are the WB image, lot number and protocol we used for kidney using anti-AMACR antibody PB9983. Let me know if you need anything else.

D. Miller

Verified customer

Asked: 2013-01-08

Answer

I appreciate the data. You have provided everything we needed. Our lab team are working to resolve your inquiry as quickly as possible, and we appreciate your patience and understanding! Please let me know if there is anything you need in the meantime.

Boster Scientific Support

Answered: 2013-01-08

Size

Conjugation

Total: $370

SKU:PB9983

In stock, 2 left.

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*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
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$50 fee for conjugation. Antibody size is reduced to 50ug.

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