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Product Info Summary
| SKU: | M02055 |
|---|---|
| Size: | 100 μl/vial |
| Reactive Species: | Human |
| Host: | Rabbit |
| Application: | IHC, WB |
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Product info
Product Name
Anti-ASAH1 Antibody (Monoclonal, 32A87)
SKU/Catalog Number
M02055
Size
100 μl/vial
Form
Liquid
Description
Boster Bio Anti-ASAH1 Antibody (Monoclonal, 32A87) catalog # M02055. Tested in WB, IHC applications. This antibody reacts with Human.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-ASAH1 Antibody (Monoclonal, 32A87) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M02055)
Host
Rabbit
Contents
Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.
Clonality
Monoclonal
Clone Number
32A87
Immunogen
Recombinant protein within human ASAH1 aa 3-393.
Reactive Species
M02055 is reactive to ASAH1 in Human
Calculated molecular weight
44.7 kDa
Background of ASAH1
The ASAH1 gene encodes in humans the acid ceramidase enzyme. It is mapped to 8p22. This gene encodes a member of the acid ceramidase family of proteins. Alternative splicing results in multiple transcript variants,at least one of which encodes a preproprotein that is proteolytically processed. Processing of this preproprotein generates alpha and beta subunits that heterodimerize to form the mature lysosomal enzyme,which catalyzes the degradation of ceramide into sphingosine and free fatty acid. This enzyme is overexpressed in multiple human cancers and may play a role in cancer progression. Mutations in this gene are associated with the lysosomal storage disorder,Farber lipogranulomatosis,and a neuromuscular disorder,spinal muscular atrophy with progressive myoclonic epilepsy.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M02055 is guaranteed for IHC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blot, 1:500-2000
Immunohistochemistry, 1:50-200
Validation Images & Assay Conditions
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Specific Publications For Anti-ASAH1 Antibody (Monoclonal, 32A87) (M02055)
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