Anti-ASM/SMPD1 Antibody (Monoclonal, 31S67)

Product Name

Anti-ASM/SMPD1 Antibody (Monoclonal, 31S67)

View all SMPD1 Antibodies

SKU/Catalog Number

M00752-1

Size

100 μl/vial

Form

Liquid

Description

Boster Bio Anti-ASM/SMPD1 Antibody (Monoclonal, 31S67) catalog # M00752-1. Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat, Monkey.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-ASM/SMPD1 Antibody (Monoclonal, 31S67) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00752-1)

Host

Rabbit

Contents

Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Clonality

Monoclonal

Clone Number

31S67

Immunogen

Recombinant protein within human Acid sphingomyelinase aa 49-629.

Reactive Species

M00752-1 is reactive to SMPD1 in Human, Monkey, Mouse, Rat

Calculated molecular weight

69.9 kDa

Background of SMPD1

Sphingomyelin phosphodiesterase 1 (SMPD1), also known as acid sphingomyelinase (ASM), is an enzyme that in humans is encoded by the SMPD1 gene. Enables acid sphingomyelin phosphodiesterase activity and zinc ion binding activity. Involved in ceramide biosynthetic process; positive regulation of apoptotic process; and response to ionizing radiation. Acts upstream of or within ceramide metabolic process; cholesterol metabolic process; and sphingomyelin catabolic process. Located in extracellular space. Is expressed in several structures, including alimentary system; integumental system; nervous system; sensory organ; and skeleton. Used to study Niemann-Pick disease. Human ortholog(s) of this gene implicated in Niemann-Pick disease; Niemann-Pick disease type A; and Niemann-Pick disease type B. Orthologous to human SMPD1 (sphingomyelin phosphodiesterase 1).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

M00752-1 is guaranteed for IHC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 1:500-2000
Immunohistochemistry, 1:50-200

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

See full target information SMPD1

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