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Product Info Summary
| SKU: | M00357-3 |
|---|---|
| Size: | 100 μl/vial |
| Reactive Species: | Mouse |
| Host: | Rabbit |
| Application: | IF, IHC, WB |
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Product info
Product Name
Anti-CD11c/Integrin Alpha X/ITGAX Antibody (Monoclonal, 34I54)
SKU/Catalog Number
M00357-3
Size
100 μl/vial
Form
Liquid
Description
Boster Bio Anti-CD11c/Integrin Alpha X/ITGAX Antibody (Monoclonal, 34I54) catalog # M00357-3. Tested in WB, IHC, IF applications. This antibody reacts with Mouse.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-CD11c/Integrin Alpha X/ITGAX Antibody (Monoclonal, 34I54) (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00357-3)
Host
Rabbit
Contents
Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.
Clonality
Monoclonal
Clone Number
34I54
Immunogen
Recombinant protein within mouse CD11c aa 618-934.
Reactive Species
M00357-3 is reactive to Itgax in Mouse
Calculated molecular weight
129.2 kDa
Background of Itgax
CD11c, also known as Integrin, alpha X (complement component 3 receptor 4 subunit) (ITGAX), is a genethat encodes for CD11c. This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
Application & Images
Applications
M00357-3 is guaranteed for IF, IHC, WB Boster Guarantee
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western blot, 1:500-2000
Immunohistochemistry, 1:50-200
Immunofluorescence, 1:50-200
Validation Images & Assay Conditions
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Specific Publications For Anti-CD11c/Integrin Alpha X/ITGAX Antibody (Monoclonal, 34I54) (M00357-3)
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