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- Table of Contents
Integrin alpha-X Antibodies
AND ITGAX ELISA kits, Integrin alpha-X Proteins
Many biological assays use antibodies to detect Integrin alpha-X, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Integrin alpha-X in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Integrin alpha-X antibodies...
Designing a Western blot for Integrin alpha-X? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the ITGAX Western Blot GuideITGAX Infographic by Boster Bio
All ITGAX Products
Product
Figures
Specificity
Applications
Price
Anti-CD11c/Itgax Antibody Picoband®
7 Citations
Mouse, Rat
ELISA, IHC, WB
$370
Cat # A00357-3
100 μg/vial
Cat # A00357-3
100 μg/vial
Anti-CD11c/ITGAX Antibody Picoband®
1 Citations
Human, Mouse
ELISA, IHC, WB
$370
Cat # A00357-1
100 μg/vial
Cat # A00357-1
100 μg/vial
ITGAX Overview
Facts about Integrin alpha-X.
Integrin alpha-X (ITGAX)
Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen.
It mediates cell-cell interaction during inflammatory reactions. It is especially important in monocyte adhesion and chemotaxis.
Gene Information
| Human | |
|---|---|
| Gene Name: | ITGAX |
| Uniprot: | P20702 |
| Entrez: | 3687 |
Family
| Belongs to: |
|---|
| integrin alpha chain family |
Alternative Names
95 alpha chain; 95; 95, alpha subunit; CD11 antigen-like family member C; CD11c antigen; CD11c; CD11Cleu M5, alpha subunit; Integrin alpha X; integrin alpha-X; integrin, alpha X (antigen CD11C (p150), alpha polypeptide); integrin, alpha X (complement component 3 receptor 4 subunit); ITGAX; Leu M5; Leukocyte adhesion glycoprotein p150; Leukocyte adhesion receptor p150; leukocyte surface antigen p150; myeloid membrane antigen, alpha subunit; p150 95 integrin alpha chain; p150,95 alpha; SLEB6
Molecular Weight
Mass (kDA):
127.829 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 16p11.2 |
| Sequence: | 16; NC_000016.10 (31355167..31382999) |
Tissue Specificity
Predominantly expressed in monocytes and granulocytes.
Subcellular Localizations
Membrane; Single-pass type I membrane protein.
Diseases
- Inflammation
- Tissue Adhesions
- Neoplasms
- Lupus Erythematosus, Systemic
- Brain Injuries
- Hypertrophy
- Diphtheria
- Collecting Duct Carcinoma Of The Kidney
- Autoimmunity
- Sclerosis
- Neoplasm Metastasis
- Hamman-rich Syndrome
- Melanoma
Interacting Proteins
- ITGB2
Pathways
- Neurogenesis
- Cell Adhesion
- Cell Activation
- Muscle Cell Migration
- Cell Migration
- Smooth Muscle Cell Migration
- Fertilization
- Aging
- T Cell Activation
- Localization
PTMs
- Disulfide bond
Research Areas
- Dendritic Cell Markers
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ITGAX
bosterbio.com/bosterbio-gene-info-cards/ITGAX
References
PMID: 3327687 by Corbi A.L., et al. cDNA cloning and complete primary structure of the alpha subunit of a leukocyte adhesion glycoprotein, p150,95.
PMID: 2303426 by Corbi A.L., et al. Genomic structure of an integrin alpha subunit, the leukocyte p150,95 molecule.
4 Publications of Boster Integrin alpha-X Antibodies & ELISA Kits
- PubMed ID: PMID:25691929, Expressions of CD11a, CD11b, and CD11c integrin proteins in rats with myocardial...
- PubMed ID: 10.1016/j.tranon.2016.12.002, Immunotherapy with Dendritic Cells Modified with Tumor-Associated Antigen Gene D...
- PubMed ID: 25691929, Mu L, Jing C, Guo Z. Iran J Basic Med Sci. 2014 Nov;17(11):874-8. Expressions Of...
- PubMed ID: 23346371, Huang J, Zhu C, Zhang P, Zhu Q, Liu Y, Zhu Z, Wang M, Li W, Yang G, Dong N, Liu ...
*More publications can be found for each product on its corresponding product page