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- Table of Contents
ODF2 Antibodies
AND ODF2 ELISA kits, ODF2 Proteins
Many biological assays use antibodies to detect ODF2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ODF2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ODF2 antibodies...
Designing an IHC experiment for ODF2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the ODF2 IHC GuideODF2 Infographic by Boster Bio
All ODF2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A05599-3
100 μg/vial
Cat # A05599-3
100 μg/vial
Human
Flow Cytometry, WB
$370
Cat # M05599
100 μl/vial
Cat # M05599
100 μl/vial
ODF2 Overview
Facts about Outer dense fiber protein 2.
Outer dense fiber protein 2 (ODF2)
Seems to be a significant component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and could help to maintain the passive elastic structures and elastic recoil of the sperm tail.
May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles.
Gene Information
| Human | |
|---|---|
| Gene Name: | ODF2 |
| Uniprot: | Q5BJF6 |
| Entrez: | 4957 |
Family
| Belongs to: |
|---|
| ODF2 family |
Alternative Names
Cenexin; FLJ44866; MGC111096; MGC9034; ODF2/1; ODF2/2; ODF8484-kD; outer dense fiber of sperm tails 2; outer dense fiber protein 2; sperm tail structural protein
Molecular Weight
Mass (kDA):
95.401 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9q34.11 |
| Sequence: | 9; NC_000009.12 (128455155..128501292) |
Tissue Specificity
Testis-specific (at protein level). Highly expressed in cytoplasm of step 2 round spermatids. Detected in the middle piece and extends to about half the principal piece of the sperm tails.
Subcellular Localizations
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle pole. Cell projection, cilium, flagellum. Localized at the microtubule organizing centers in interphase and spindle poles in mitosis. Localized at the distal/subdistal appendages of mother centrioles.
Diseases
- Malignant Neoplasms
- Infertility
- Neoplasms
- Malignant Neoplasm Of Prostate
- Prostatic Neoplasms
- Autoimmune Reaction
- Basal Cell Carcinoma
- Autoimmunity
- Disease Of Adrenal Medulla
- Neoplasm Metastasis
- Adult Acute Lymphocytic Leukemia
- Retinal Degeneration
Interacting Proteins
- CCDC120
Pathways
- Localization
- Spermatogenesis
- Transport
- Cell Motility
- Cell Cycle
- Cell Development
- Germ Cell Development
- Reproductive Process
- Fertilization
- Microtubule Nucleation
- Sperm Motility
- Pachytene
- Microtubule Anchoring
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ODF2
bosterbio.com/bosterbio-gene-info-cards/ODF2
References
PMID: 10381817 by Petersen C., et al. Outer dense fibre proteins from human sperm tail: molecular cloning and expression analyses of two cDNA transcripts encoding proteins of approximately 70 kDa.
PMID: 16966375 by Soung N.-K., et al. Requirement of hCenexin for proper mitotic functions of polo-like kinase 1 at the centrosomes.