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- Table of Contents
Collagen alpha-2(I) chain Antibodies
AND COL1A2 ELISA kits, Collagen alpha-2(I) chain Proteins
Many biological assays use antibodies to detect Collagen alpha-2(I) chain, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Collagen alpha-2(I) chain in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Collagen alpha-2(I) chain antibodies...
Designing a Western blot for Collagen alpha-2(I) chain? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the COL1A2 Western Blot GuideDesigning an IHC experiment for Collagen alpha-2(I) chain? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the COL1A2 IHC GuideCOL1A2 Infographic by Boster Bio
All COL1A2 Products
Product
Figures
Specificity
Applications
Price
Anti-Collagen alpha-2(I) chain COL1A2 Antibody
7 Citations
Human, Mouse, Rat
ELISA, IF, IHC, WB
$399
Cat # A00624-1
100μl
Cat # A00624-1
100μl
Human
ELISA
$480
Cat # EKC1127
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1127
1 kit, containing one 96-well plate and all necessary reagents
COL1A2 Overview
Facts about Collagen alpha-2(I) chain.
Collagen alpha-2(I) chain (COL1A2)
Type I collagen is a member of group I collagen (fibrillar forming collagen). .
Gene Information
| Human | |
|---|---|
| Gene Name: | COL1A2 |
| Uniprot: | P08123 |
| Entrez: | 1278 |
Family
| Belongs to: |
|---|
| fibrillar collagen family |
Alternative Names
alpha 2(I)-collagen; Alpha-2 type I collagen; collagen alpha-2(I) chain; collagen I, alpha-2 polypeptide; collagen of skin, tendon and bone, alpha-2 chain; collagen, type I, alpha 2; OI4; osteogenesis imperfecta type IV; type I procollagen
Molecular Weight
Mass (kDA):
129.314 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q21.3 |
| Sequence: | 7; NC_000007.14 (94394895..94431227) |
Tissue Specificity
Forms the fibrils of tendon, ligaments and bones. In bones the fibrils are mineralized with calcium hydroxyapatite.
Subcellular Localizations
Secreted, extracellular space, extracellular matrix.
Diseases
- Osteogenesis Imperfecta
- Fibrosis
- Fracture
- Neoplasms
- Connective Tissue Diseases
- Diffuse Scleroderma
- Ehlers-danlos Syndrome
- Sclerosis
- Malignant Neoplasms
- Scleroderma
- Osteoporosis
- Dentinogenesis Imperfecta
- Bone Diseases
Interacting Proteins
- KCNIP4
- SGTA
- SGTB
- UBQLN1
Pathways
- Pathogenesis
- Dentinogenesis
- Methylation
- Localization
- Secretion
- Wound Healing
- Cell Growth
- Cell Proliferation
- Aging
- Dna Methylation
- Translation
- Reverse Transcription
- Ossification
PTMs
- Phosphorylation
- Cleavage
- Methylation
- Acetylation
- Hydroxylation
- Deacetylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/COL1A2
bosterbio.com/bosterbio-gene-info-cards/COL1A2
References
PMID: 2824475 by de Wet W.J., et al. Organization of the human pro-alpha 2(I) collagen gene.
PMID: 9016532 by Dalgleish R.; The human type I collagen mutation database.