Anti-DIS3 Antibody

DIS3 antibody

Boster Bio Anti-DIS3 Antibody catalog # A01736-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A01736-1
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ELISA, IHC, WB

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Product Name

Anti-DIS3 Antibody

View all DIS3 Antibodies

SKU/Catalog Number

A01736-1

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-DIS3 Antibody catalog # A01736-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-DIS3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01736-1)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E. coli-derived human DIS3 recombinant protein (Position: Q62-A304).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A01736-1 is reactive to DIS3 in Human, Mouse, Rat

Applications

A01736-1 is guaranteed for ELISA, IHC, WB Boster Guarantee

Observed Molecular Weight

109 kDa

Calculated molecular weight

109.003kDa

Background of DIS3

Exosome complex exonuclease RRP44 or Dis3 is an enzyme that in humans is encoded by the DIS3 gene. Its protein product is an RNase enzyme homologous to the yeast protein Rrp44, and can be part of the exosome complex in the nucleus of eukaryotic cells. By genomic sequence analysis, this gene is mapped to chromosome 13q21-q22. Expression of human DIS3 could partially complement Dis3 depletion in yeast.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.1-0.5μg/ml
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml
ELISA, 0.1-0.5μg/ml

Validation Images & Assay Conditions

Gene/Protein Information For DIS3 (Source: Uniprot.org, NCBI)

Gene Name

DIS3

Full Name

Exosome complex exonuclease RRP44

Weight

109.003kDa

Superfamily

RNR ribonuclease family

Alternative Names

2810028N01Rik; DIS3 mitotic control homolog (S. cerevisiae); dis3p; DKFZp667L1817; EC 3.1.13; EC 3.1.13.-; EC 3.1.26.-; EXOSC11; exosome complex exonuclease RRP44; exosome component 11; FLJ10484; KIAA1008RP11-342J4.3; MGC33035; mitotic control protein dis3 homolog; Protein DIS3 homolog; Ribosomal RNA-processing protein 44; RRP44bA555G22.1 DIS3 2810028N01Rik, EXOSC11, KIAA1008, RRP44, dis3p DIS3 homolog, exosome endoribonuclease and 3-5 exoribonuclease exosome complex exonuclease RRP44|DIS3 exosome endoribonuclease and 3-5 exoribonuclease|DIS3 mitotic control homolog|exosome component 11|mitotic control protein dis3 homolog|ribosomal RNA-processing protein 44

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on DIS3, check out the DIS3 Infographic

DIS3 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for DIS3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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3 Customer Q&As for Anti-DIS3 Antibody

Question

Is a blocking peptide available for product anti-DIS3 antibody (A01736-1)?

Verified Customer

Verified customer

Asked: 2019-11-28

Answer

We do provide the blocking peptide for product anti-DIS3 antibody (A01736-1). If you would like to place an order for it please contact [email protected] and make a special request.

Boster Scientific Support

Answered: 2019-11-28

Question

Will anti-DIS3 antibody A01736-1 work on goat IHC-P with brain peripheral blood leukocyte?

Verified Customer

Verified customer

Asked: 2019-05-27

Answer

Our lab technicians have not validated anti-DIS3 antibody A01736-1 on goat. You can run a BLAST between goat and the immunogen sequence of anti-DIS3 antibody A01736-1 to see if they may cross-react. If the sequence homology is close, then you can perform a pilot test. Keep in mind that since we have not validated goat samples, this use of the antibody is not covered by our guarantee. However we have an innovator award program that if you test this antibody and show it works in goat brain peripheral blood leukocyte in IHC-P, you can get your next antibody for free.

Boster Scientific Support

Answered: 2019-05-27

Question

We are currently using anti-DIS3 antibody A01736-1 for mouse tissue, and we are happy with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it likely that the antibody can work on pig tissues as well?

Verified Customer

Verified customer

Asked: 2019-02-28

Answer

The anti-DIS3 antibody (A01736-1) has not been tested for cross reactivity specifically with pig tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in pig you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2019-02-28

Order DetailsPrice
A01736-1

100μg

$370
A01736-1-10ug

10μg sample (liquid)

$99
A01736-1-Biotin

100 μg Biotin conjugated

$570
A01736-1-Cy3

100 μg Cy3 conjugated

$570
A01736-1-Dylight488

100 μg Dylight488 conjugated

$570
A01736-1-Dylight550

100 μg Dylight550 conjugated

$570
A01736-1-Dylight594

100 μg Dylight594 conjugated

$570
A01736-1-FITC

100 μg FITC conjugated

$570
A01736-1-HRP

100 μg HRP conjugated

$570
A01736-1-APC

100 μg APC conjugated

$670
A01736-1-PE

100 μg PE conjugated

$670
A01736-1-carrier-free

Carrier Free

$370

More conjugates/formats

Free Secondary Antibody

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A01736-1
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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