Anti-Dopamine Receptor D1/DRD1 Antibody

Dopamine D1R/DRD1 antibody

Boster Bio Anti-Dopamine Receptor D1/DRD1 Antibody catalog # PA1571. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: PA1571
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IHC, WB

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Product Name

Anti-Dopamine Receptor D1/DRD1 Antibody

View all Dopamine D1R/DRD1 Antibodies

SKU/Catalog Number

PA1571

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Dopamine Receptor D1/DRD1 Antibody catalog # PA1571. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Dopamine Receptor D1/DRD1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1571)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human DRD1, different from the related rat and mouse sequences by one amino acid.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA1571 is reactive to DRD1 in Human, Mouse, Rat

Applications

PA1571 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

130 kDa

Calculated molecular weight

49.293kDa

Background of Dopamine D1R/DRD1

Dopamine receptor D1, also known as DRD1, is a human gene. It is the most highly expressed DA receptor subtype among the DA receptor family. Receptors for dopamine have been classified into two functional types, D1 and D2. They belong to the family of receptors acting through G (or guanine nucleotide-binding) proteins. D2 receptors inhibit adenylyl cyclase, but D1 receptors stimulate adenylyl cyclase and activate cyclic AMP-dependent protein kinases. Dopamine D1 and D2 receptors are targets of drug therapy in many psychomotor disorders, including Parkinson's disease and schizophrenia, and may also have a role in drug addiction and alcoholism. D1 receptors regulate neuron growth and differentiation, influence behaviour and modify dopamine D2 receptor-mediated events. And the presence of a D1 receptor gene restriction fragment length polymorphism will be helpful for future disease linkage studies. DRD1 also regulates the neurochemical architecture of the striatum and is critical for the normal expression of motor activity.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Rat, Mouse, By Heat
Western blot, 0.1-0.5μg/ml, Human, Rat, Mouse

Validation Images & Assay Conditions

Gene/Protein Information For DRD1 (Source: Uniprot.org, NCBI)

Gene Name

DRD1

Full Name

D(1A) dopamine receptor

Weight

49.293kDa

Superfamily

G-protein coupled receptor 1 family

Alternative Names

D(1A) dopamine receptor; D1DR; DADR; Dopamine D1 R; Dopamine D1 receptor; Dopamine D1R; dopamine receptor D1; DRD1; DRD1A DRD1 DADRA, DRD1 dopamine receptor D1 D(1A) dopamine receptor|dopamine D1 receptor

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on DRD1, check out the DRD1 Infographic

DRD1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for DRD1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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1 Customer Q&As for Anti-Dopamine Receptor D1/DRD1 Antibody

Question

We are currently using anti-Dopamine Receptor D1/DRD1 antibody PA1571 for human tissue, and we are happy with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it likely that the antibody can work on dog tissues as well?

Verified Customer

Verified customer

Asked: 2017-12-26

Answer

The anti-Dopamine Receptor D1/DRD1 antibody (PA1571) has not been validated for cross reactivity specifically with dog tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in dog you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2017-12-26

Order DetailsPrice
PA1571

100μg

$370
PA1571-10ug

10μg sample (liquid)

$99
PA1571-Biotin

100 μg Biotin conjugated

$570
PA1571-Cy3

100 μg Cy3 conjugated

$570
PA1571-Dylight488

100 μg Dylight488 conjugated

$570
PA1571-Dylight550

100 μg Dylight550 conjugated

$570
PA1571-Dylight594

100 μg Dylight594 conjugated

$570
PA1571-FITC

100 μg FITC conjugated

$570
PA1571-HRP

100 μg HRP conjugated

$570
PA1571-APC

100 μg APC conjugated

$670
PA1571-PE

100 μg PE conjugated

$670
PA1571-carrier-free

Carrier Free

$370

More conjugates/formats

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Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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