Anti-DUSP6 Antibody Picoband™

MKP-3/DUSP6 antibody

Boster Bio Anti-DUSP6 Antibody Picoband™ catalog # A02157-2. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Info Summary

SKU: A02157-2
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: ELISA, Flow Cytometry, IF, IHC, ICC, WB

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Product Name

Anti-DUSP6 Antibody Picoband™

View all MKP-3/DUSP6 Antibodies

SKU/Catalog Number

A02157-2

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-DUSP6 Antibody Picoband™ catalog # A02157-2. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Cite This Product

Anti-DUSP6 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02157-2)

Host

Rabbit

Contents

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human DUSP6 recombinant protein (Position: M1-T381).

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins.

Reactive Species

A02157-2 is reactive to DUSP6 in Human, Mouse, Rat

Applications

A02157-2 is guaranteed for ELISA, Flow Cytometry, IF, IHC, ICC, WB Boster Guarantee

Observed Molecular Weight

50 kDa

Calculated molecular weight

42.32kDa

Background of MKP-3/DUSP6

Dual specificity phosphatase 6 (DUSP6) is an enzyme that in humans is encoded by the DUSP6 gene. The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Mutations in this gene have been associated with congenital hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been found for this gene.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Flow Cytometry, 1-3 μg/1x106 cells, Human
Direct ELISA, 0.1-0.5 μg/ml, Human

Validation Images & Assay Conditions

Gene/Protein Information For DUSP6 (Source: Uniprot.org, NCBI)

Gene Name

DUSP6

Full Name

Dual specificity protein phosphatase 6

Weight

42.32kDa

Superfamily

protein-tyrosine phosphatase family

Alternative Names

dual specificity phosphatase 6; Dual specificity protein phosphatase PYST1; DUSP6; EC 3.1.3.16; EC 3.1.3.48; MAP kinase phosphatase 3; Mitogen-activated protein kinase phosphatase 3; MKP3; MKP-3; MKP3serine/threonine specific protein phosphatase; PYST1; PYST1dual specificity protein phosphatase 6 DUSP6 HH19, MKP3, PYST1 dual specificity phosphatase 6 dual specificity protein phosphatase 6|MAP kinase phosphatase 3|dual specificity protein phosphatase PYST1|mitogen-activated protein kinase phosphatase 3|serine/threonine specific protein phosphatase

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on DUSP6, check out the DUSP6 Infographic

DUSP6 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for DUSP6: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A02157-2

100μg

$370
A02157-2-10ug

10μg sample (liquid)

$99
A02157-2-Biotin

100 μg Biotin conjugated

$570
A02157-2-Cy3

100 μg Cy3 conjugated

$570
A02157-2-Dylight488

100 μg Dylight488 conjugated

$570
A02157-2-Dylight550

100 μg Dylight550 conjugated

$570
A02157-2-Dylight594

100 μg Dylight594 conjugated

$570
A02157-2-FITC

100 μg FITC conjugated

$570
A02157-2-HRP

100 μg HRP conjugated

$570
A02157-2-APC

100 μg APC conjugated

$670
A02157-2-PE

100 μg PE conjugated

$670
A02157-2-carrier-free

Carrier Free

$370

More conjugates/formats

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A02157-2
Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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