Anti-Dynamin-1-like protein DNM1L Antibody

Product Name

Anti-Dynamin-1-like protein DNM1L Antibody

View all DNM1L Antibodies

SKU/Catalog Number

A00556

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Dynamin-1-like protein DNM1L Antibody (Catalog # A00556). Tested in ELISA, WB, ICC, IF applications. This antibody reacts with Human, Mouse.

Storage & Handling

DNM1L antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Cite This Product

Anti-Dynamin-1-like protein DNM1L Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A00556)

Host

Rabbit

Contents

DNM1L antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

DNM1L antibody was raised against a 19 amino acid peptide near the center of human DNM1L. The immunogen is located within amino acids 530 - 580 of DNM1L.

Cross-reactivity

DNM1L antibody is human and mouse reactive. At least four isoforms of DNM1L are known to exist; this antibody will detect the two longest isoforms.

Reactive Species

A00556 is reactive to DNM1L in Human, Mouse

Observed Molecular Weight

68 kDa

Calculated molecular weight

81.9 kDa

Background of DNM1L

The Dynamin-1-like protein (DNM1L) is a member of the dynamin superfamily of GTPases (1). DNM1L mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis (2). Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF) (3).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Applications

A00556 is guaranteed for ELISA, IF, ICC, WB Boster Guarantee

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

DNM1L antibody can be used for detection of DNM1L by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunocytochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

See full target information DNM1L

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