Anti-Glutamate Receptor 1/GRIA1 Antibody Picoband™

GluR1 antibody

Boster Bio Anti-Glutamate Receptor 1/GRIA1 Antibody Picoband™ catalog # PB9204. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. Cited in 3 publication(s).

Product Info Summary

SKU: PB9204
Size: 100 μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IHC, WB

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Product Name

Anti-Glutamate Receptor 1/GRIA1 Antibody Picoband™

View all GluR1 Antibodies

SKU/Catalog Number

PB9204

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Glutamate Receptor 1/GRIA1 Antibody Picoband™ catalog # PB9204. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Glutamate Receptor 1/GRIA1 Antibody Picoband™ (Boster Biological Technology, Pleasanton CA, USA, Catalog # PB9204)

Host

Rabbit

Contents

Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

E.coli-derived human GRIA1 recombinant protein (Position: A19-R360). Human GRIA1 shares 98% amino acid (aa) sequence identity with both mouse and rat GRIA1.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PB9204 is reactive to GRIA1 in Human, Mouse, Rat

Applications

PB9204 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

101 kDa

Calculated molecular weight

101.506kDa

Background of GluR1

GLUR1, Glutamate receptor 1, is a protein that in humans is encoded by the GLUR1 gene. GLUR1 mRNA is widely expressed in human brain. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The GRIA1 belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Each of the members (GRIA1-4) include flip and flop isoforms generated by alternative RNA splicing. The receptor subunits encoded by each isoform vary in their signal transduction properties. The isoform presented here is the flop isoform. In situ hybridization experiments showed that human GRIA1 mRNA is present in granule and pyramidal cells in the hippocampal formation.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Mouse, Rat, By Heat
Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat

Validation Images & Assay Conditions

Gene/Protein Information For GRIA1 (Source: Uniprot.org, NCBI)

Gene Name

GRIA1

Full Name

Glutamate receptor 1

Weight

101.506kDa

Superfamily

glutamate-gated ion channel (TC 1.A.10.1) family

Alternative Names

AMPA 1; AMPA-selective glutamate receptor 1; GluA1; GLUH1; GluR1; gluR-1; GLUR1gluR-A; GLURA; GluR-A; gluR-K1; glutamate receptor 1; Glutamate receptor ionotropic, AMPA 1; glutamate receptor, ionotropic, AMPA 1; GRIA1; HBGR1; MGC133252 GRIA1 GLUH1, GLUR1, GLURA, GluA1, HBGR1 glutamate ionotropic receptor AMPA type subunit 1 glutamate receptor 1|AMPA 1|AMPA-selective glutamate receptor 1|gluR-1|gluR-A|gluR-K1|glutamate receptor, ionotropic, AMPA 1

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on GRIA1, check out the GRIA1 Infographic

GRIA1 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for GRIA1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

PB9204 has been cited in 3 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Loss of the golgin GM130 causes Golgi disruption, Purkinje neuron loss, and ataxia in mice

Disruption of glutamate neurotransmitter transmission is modulated by SNAP-25 in benzo[a]pyrene-induced neurotoxic effects

Loss of the golgin GM130 causes Golgi disruption, Purkinje neuron loss, and ataxia in mice

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1 Customer Q&As for Anti-Glutamate Receptor 1/GRIA1 Antibody Picoband™

Question

We are currently using anti-Glutamate Receptor 1/GRIA1 antibody PB9204 for human tissue, and we are well pleased with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it possible that the antibody can work on horse tissues as well?

Verified Customer

Verified customer

Asked: 2019-12-12

Answer

The anti-Glutamate Receptor 1/GRIA1 antibody (PB9204) has not been validated for cross reactivity specifically with horse tissues, though there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in horse you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2019-12-12

Order DetailsPrice
PB9204

100μg

$370
PB9204-10ug

10μg sample (liquid)

$99
PB9204-Biotin

100 μg Biotin conjugated

$570
PB9204-Cy3

100 μg Cy3 conjugated

$570
PB9204-Dylight488

100 μg Dylight488 conjugated

$570
PB9204-Dylight550

100 μg Dylight550 conjugated

$570
PB9204-Dylight594

100 μg Dylight594 conjugated

$570
PB9204-FITC

100 μg FITC conjugated

$570
PB9204-HRP

100 μg HRP conjugated

$570
PB9204-APC

100 μg APC conjugated

$670
PB9204-PE

100 μg PE conjugated

$670
PB9204-carrier-free

Carrier Free

$370

More conjugates/formats

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Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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