Anti-Haptoglobin/HP Antibody

Haptoglobin antibody

Boster Bio Anti-Haptoglobin/HP Antibody catalog # PA1599. Tested in IHC, WB applications. This antibody reacts with Human. Cited in 1 publication(s).

Product Info Summary

SKU: PA1599
Size: 100 μg/vial
Reactive Species: Human
Host: Rabbit
Application: IHC, WB

Product Name

Anti-Haptoglobin/HP Antibody

View all Haptoglobin Antibodies

SKU/Catalog Number

PA1599

Size

100 μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Haptoglobin/HP Antibody catalog # PA1599. Tested in IHC, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Haptoglobin/HP Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1599)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Isotype

Rabbit IgG

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human Haptoglobin.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross-reactivity with other proteins

Reactive Species

PA1599 is reactive to HP in Human

Applications

PA1599 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

45 kDa

Calculated molecular weight

45.205kDa

Background of Haptoglobin

Haptoglobin (HP), is a protein that in humans is encoded by the HP gene. Haptoglobin, a plasma glycoprotein that binds free hemoglobin, has a tetrameric structure of 2 alpha and 2 beta polypeptides that are covalently associated by disulfide bonds. Haptoglobin is homologous to serine proteases of the chymotrypsinogen family. In the chimpanzee, there are 3 genes in the haptoglobin family (haptoglobin, HP; haptoglobin-related, HPR; and haptoglobin-primate, HPP), whereas only 2 genes exist in humans (HP and HPR). There are similarities between the primary structures of the alpha chain and of light chains of gamma globulins. The alpha haptoglobin locus is on the long arm of chromosome 16, where its exact cytogenetic location is 16q22.2. A major function of haptoglobin is to bind hemoglobin (Hb) to form a stable Hp-Hb complex and thereby prevent Hb-induced oxidative tissue damage. Haptoglobin is an unusual secretory protein in that it is proteolytically processed in the endoplasmic reticulum and not in the Golgi. The human haptoglobin HP*2 allele contains a 1.7-kb intragenic duplication that arose after a unique nonhomologous recombination between the prototype HP*1 alleles.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat
Western blot, 0.1-0.5μg/ml, Human

Validation Images & Assay Conditions

Gene/Protein Information For HP (Source: Uniprot.org, NCBI)

Gene Name

HP

Full Name

Haptoglobin

Weight

45.205kDa

Superfamily

peptidase S1 family

Alternative Names

binding peptide; BP; haptoglobin alpha(1S)-beta; haptoglobin alpha(2FS)-beta; Haptoglobin; haptoglobin, alpha polypeptide; haptoglobin, beta polypeptide; HP; HP-1; hp2-alpha; HP2ALPHA2; HPA1S; MGC111141; zonulin HP BP2ALPHA2, HPA1S, HP haptoglobin haptoglobin|binding peptide|haptoglobin alpha(1S)-beta|haptoglobin alpha(2FS)-beta|haptoglobin, alpha polypeptide|haptoglobin, beta polypeptide|zonulin

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on HP, check out the HP Infographic

HP infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for HP: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

Hello CJ!

PA1599 has been cited in 1 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Identification of a protein associated with the activity of cytokine-induced killer cells

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Order DetailsPrice
PA1599

100μg

$370
PA1599-10ug

10μg sample (liquid)

$99
PA1599-Biotin

100 μg Biotin conjugated

$570
PA1599-Cy3

100 μg Cy3 conjugated

$570
PA1599-Dylight488

100 μg Dylight488 conjugated

$570
PA1599-Dylight550

100 μg Dylight550 conjugated

$570
PA1599-Dylight594

100 μg Dylight594 conjugated

$570
PA1599-FITC

100 μg FITC conjugated

$570
PA1599-HRP

100 μg HRP conjugated

$570
PA1599-APC

100 μg APC conjugated

$670
PA1599-PE

100 μg PE conjugated

$670
PA1599-carrier-free

Carrier Free

$370

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Buy one primary antibody get one 0.5ml HRP or Biotin secondary antibody for free.
*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
$370.00

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