Anti-Hrs (L330) HGS Antibody

HGS antibody

Boster Bio Anti-Hrs (L330) HGS Antibody catalog # A01174. Tested in WB,IHC,IF applications. This antibody reacts with Human,Mouse,Rat.

Product Info Summary

SKU: A01174
Size: 100ul
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IF, IHC, WB

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Product Name

Anti-Hrs (L330) HGS Antibody

View all HGS Antibodies

SKU/Catalog Number

A01174

Size

100ul

Form

Liquid

Description

Boster Bio Anti-Hrs (L330) HGS Antibody catalog # A01174. Tested in WB,IHC,IF applications. This antibody reacts with Human,Mouse,Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Hrs (L330) HGS Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01174)

Host

Rabbit

Contents

Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from human GCN2 around the phosphorylation site of T899.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A01174 is reactive to HGS in Human, Mouse, Rat

Applications

A01174 is guaranteed for IF, IHC, WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

86.192kDa

Background of HGS

Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region.

ShunJiang Yu, J. Biol. Chem., May 2003; 278: 19597 - 19602.
TT Chen, Mol. Cell. Biol., Jun 1997; 17: 3056 - 3064.
Oscar B. Goodman, J. Biol. Chem., Oct 1995; 270: 23768.
Didier Jean, J. Biol. Chem., Jun 1998; 273: 16501

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB: 1:500-1:1000
IHC: 1:50-1:200
IF: 1:50-1:200

Validation Images & Assay Conditions

There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.

Gene/Protein Information For HGS (Source: Uniprot.org, NCBI)

Gene Name

HGS

Full Name

Hepatocyte growth factor-regulated tyrosine kinase substrate

Weight

86.192kDa

Alternative Names

FLJ39878; hepatocyte growth factor-regulated tyrosine kinase substrate; Hrs; HRSFLJ11421; human growth factor-regulated tyrosine kinase substrate; Protein pp110; Vps27; ZFYVE8 HGS HRS hepatocyte growth factor-regulated tyrosine kinase substrate hepatocyte growth factor-regulated tyrosine kinase substrate|human growth factor-regulated tyrosine kinase substrate|protein pp110

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on HGS, check out the HGS Infographic

HGS infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for HGS: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
A01174-100ul

100ul

$405

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*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
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