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Product Info Summary
| SKU: | M01898 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Cow, Ferret, Human, Rabbit |
| Host: | Mouse |
| Application: | Flow Cytometry, IP, IHC-P, WB |
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Product info
Product Name
Anti-Hu CD88 Purified C5AR1 Monoclonal Antibody
View all Complement Component C5aR1 Antibodies
SKU/Catalog Number
M01898
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Hu CD88 Purified C5AR1 Monoclonal Antibody (Catalog# M01898). Tested in Flow Cytometry, IP, WB, IHC-P application(s). This antibody reacts with Rabbit, Ferret, Cow, Human.
Storage & Handling
Store at 2-8°C. Do not freeze.
Cite This Product
Anti-Hu CD88 Purified C5AR1 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M01898)
Host
Mouse
Contents
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Clonality
Monoclonal
Clone Number
S5/1
Isotype
Mouse IgG2a kappa
Immunogen
Recombinant N-terminal peptide (Asp15-Asp27) of human C5aR. The mouse monoclonal antibody S5/1 recognizes an extracellular epitope of CD88 protein, a 43 kDa receptor of C5a component of the complement cascade.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
This antibody does not cross-react with Thy-1.1 alloantigen.
Reactive Species
M01898 is reactive to C5AR1 in Cow, Ferret, Human, Rabbit
Applications
M01898 is guaranteed for Flow Cytometry, IP, IHC-P, WB Boster Guarantee
Observed Molecular Weight
42 kDa
Calculated molecular weight
39.336kDa
Background of Complement Component C5aR1
CD88 / C5aR is a G protein-coupled seven membrane-spanning protein serving as a receptor for C5a component of the complement cascade, and is expressed mainly by monocytes, macrophages, neutrophils, eosinophils, and mast cells, but also e.g. by hepatocytes, glial cells, vascular endothelial cells, or cardiomyocytes. The binding of C5a to CD88 is associated with inflammatory response, including superoxide anion production, chemotaxis, and increased production of acute phase proteins. Expression of CD88 on synovial mast cells and their C5a-mediated degranulation plays a role in pathogenesis of rheumatoid arthritis.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Flow cytometry: 3-12 μg/ml.
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For C5AR1 (Source: Uniprot.org, NCBI)
Gene Name
C5AR1
Full Name
C5a anaphylatoxin chemotactic receptor 1
Weight
39.336kDa
Superfamily
G-protein coupled receptor 1 family
Alternative Names
C5a anaphylatoxin chemotactic receptor; C5A; C5aR; C5a-R; C5AR1; C5ARC5a anaphylatoxin receptor; C5R1C5a ligand; CD88 antigen; CD88; complement component 5 receptor 1 (C5a ligand); complement component 5 receptor 1; complement component 5a receptor 1; Complement Component C5a R1; Complement Component C5aR1 C5AR1 C5A, C5AR, C5R1, CD88 complement C5a receptor 1 C5a anaphylatoxin chemotactic receptor 1|C5a anaphylatoxin receptor|C5a ligand|C5a-R|complement component 5a receptor 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on C5AR1, check out the C5AR1 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for C5AR1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Hu CD88 Purified C5AR1 Monoclonal Antibody (M01898)
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No publications found for M01898
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