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- Table of Contents
C5AR1 Antibodies
AND C5AR1 ELISA kits, C5AR1 Proteins
Many biological assays use antibodies to detect C5AR1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with C5AR1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop C5AR1 antibodies...
Designing an IHC experiment for C5AR1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the C5AR1 IHC GuideC5AR1 Infographic by Boster Bio
All C5AR1 Products
Product
Figures
Specificity
Applications
Price
Anti-C5a-R/C5ar1 Antibody Picoband®
3 Citations
Mouse
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A01898-2
100 μg/vial
Cat # A01898-2
100 μg/vial
Anti-C5aR Antibody
1 Citations
Human
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01898-3
100 μl/vial
Cat # A01898-3
100 μl/vial
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01898-1
100 μg
Cat # M01898-1
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01898-3
100 μg
Cat # M01898-3
100 μg
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01898-2
100 μg
Cat # M01898-2
100 μg
Human
ELISA
$480
Cat # EKC1103
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1103
1 kit, containing one 96-well plate and all necessary reagents
C5AR1 Overview
Facts about C5a anaphylatoxin chemotactic receptor 1.
C5a anaphylatoxin chemotactic receptor 1 (C5AR1)
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520, PubMed:29300009).
The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N- terminus, and another site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099).Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion generation (PubMed:10636859, PubMed:15153520). .
Gene Information
| Human | |
|---|---|
| Gene Name: | C5AR1 |
| Uniprot: | P21730 |
| Entrez: | 728 |
Family
| Belongs to: |
|---|
| G-protein coupled receptor 1 family |
Alternative Names
C5a anaphylatoxin chemotactic receptor; C5A; C5aR; C5a-R; C5AR1; C5ARC5a anaphylatoxin receptor; C5R1C5a ligand; CD88 antigen; CD88; complement component 5 receptor 1 (C5a ligand); complement component 5 receptor 1; complement component 5a receptor 1; Complement Component C5a R1; Complement Component C5aR1
Molecular Weight
Mass (kDA):
39.336 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19q13.32 |
| Sequence: | 19; NC_000019.10 (47309861..47322066) |
Subcellular Localizations
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle. Phosphorylated C5aR colocalizes with ARRB1 and ARRB2 in cytoplasmic vesicles.
Diseases
- Inflammation
- Arthritis
- Rheumatoid Arthritis
- Systemic Infection
- Inflammatory Response
- Malignant Neoplasms
- Autoimmune Diseases
- Asthma
- Allergy
- Infective Disorder
- Pertussis
- Familial Mediterranean Fever
Pathways
- Complement Activation
- Chemotaxis
- Inflammatory Response
- Pathogenesis
- Phagocytosis
- Cell Migration
- Secretion
- Hypersensitivity
- Neutrophil Chemotaxis
- Localization
- Coagulation
- Transport
- Programmed Cell Death
PTMs
- Phosphorylation
- Formylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/C5AR1
bosterbio.com/bosterbio-gene-info-cards/C5AR1
References
PMID: 2007135 by Boulay F., et al. Expression cloning of a receptor for C5a anaphylatoxin on differentiated HL-60 cells.
PMID: 1847994 by Gerard N.P., et al. The chemotactic receptor for human C5a anaphylatoxin.