Anti-Hydroxysteroid (17-beta) Dehydrogenase 4/HSD17B4 Antibody

Boster Bio Anti-Hydroxysteroid (17-beta) Dehydrogenase 4/HSD17B4 Antibody catalog # PA1727. Tested in IHC-P, WB applications. This antibody reacts with Human, Mouse, Rat. Cited in 1 publication(s).

Product Info Summary

SKU: PA1727
Size: 100μg/vial
Reactive Species: Human, Mouse, Rat
Host: Rabbit
Application: IHC-P, WB

Product Name

Anti-Hydroxysteroid (17-beta) Dehydrogenase 4/HSD17B4 Antibody

See all HSD17B4 products

SKU/Catalog Number

PA1727

Size

100μg/vial

Form

Lyophilized

Description

Boster Bio Anti-Hydroxysteroid (17-beta) Dehydrogenase 4/HSD17B4 Antibody catalog # PA1727. Tested in IHC-P, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Hydroxysteroid (17-beta) Dehydrogenase 4/HSD17B4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1727)

Host

Rabbit

Contents

Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Clonality

Polyclonal

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human Hydroxysteroid (17-beta) Dehydrogenase 4 (744-761aa NIMLSQKLQMILKDYAKL), identical to the related rat and mouse sequences.

Cross Reactivity

No cross reactivity with other proteins

Reactive Species

PA1727 is reactive to HSD17B4 in Human, Mouse, Rat

Applications

PA1727 is guaranteed for IHC-P, WB Boster Guarantee

*Blocking peptide can be purchased at $150. Contact us for more information.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Reconsitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Mouse, Rat, By Heat
Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat

Validation Images & Assay Conditions

Gene/Protein Information For HSD17B4 (Source: Uniprot.Org, NCBI)

Uniprot ID

P51659

Gene ID

3295

Gene Name

HSD17B4

Full Name

Peroxisomal multifunctional enzyme type 2

Weight

79.686kDa

Superfamily

short-chain dehydrogenases/reductases (SDR) family

Alternative Names

12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase; 7-alpha; D-bifunctional protein; EDH17B4; hydroxysteroid (17-beta) dehydrogenase 4; MPF-2; peroxisomal multifunctional enzyme type 2,17-beta-HSD IV; peroxisomal multifunctional protein 2,17beta-estradiol dehydrogenase type IV; peroxisomal; short chain dehydrogenase/reductase family 8C, member 1,3-alpha HSD17B4 DBP, MFE-2, MFP-2, MPF-2, PRLTS1, SDR8C1 hydroxysteroid 17-beta dehydrogenase 4 peroxisomal multifunctional enzyme type 2|17-beta-HSD 4|17-beta-HSD IV|17-beta-hydroxysteroid dehydrogenase 4|17beta-estradiol dehydrogenase type IV|3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase|D-3-hydroxyacyl-CoA dehydratase|D-bifunctional protein, peroxisomal|beta-hydroxyacyl dehydrogenase|beta-keto-reductase|epididymis secretory sperm binding protein|hydroxysteroid dehydrogenase 4|multifunctional protein 2|peroxisomal multifunctional protein 2|short chain dehydrogenase/reductase family 8C member 1

*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".

For more info on HSD17B4, check out the HSD17B4 Infographic

HSD17B4 infographic

We have 30,000+ of these available, one for each gene! check them out.

In this infographic you will see the following information for HSD17B4: database IDs, super-family, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us [email protected]

PA1727 has been cited in 1 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

Correlation between HSD17B4 expression in rat liver cancer tissues and inflammation or proliferation.

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1 Customer Q&As for Anti-Hydroxysteroid (17-beta) Dehydrogenase 4/HSD17B4 Antibody

Question

We are currently using anti-Hydroxysteroid (17-beta) Dehydrogenase 4/HSD17B4 antibody PA1727 for rat tissue, and we are satisfied with the WB results. The species of reactivity given in the datasheet says human, mouse, rat. Is it possible that the antibody can work on zebrafish tissues as well?

Verified Customer

Verified customer

Asked: 2020-04-20

Answer

The anti-Hydroxysteroid (17-beta) Dehydrogenase 4/HSD17B4 antibody (PA1727) has not been tested for cross reactivity specifically with zebrafish tissues, but there is a good chance of cross reactivity. We have an innovator award program that if you test this antibody and show it works in zebrafish you can get your next antibody for free. Please contact me if I can help you with anything.

Boster Scientific Support

Answered: 2020-04-20

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