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- Table of Contents
HSD17B4 Antibodies
AND HSD17B4 ELISA kits, HSD17B4 Proteins
Many biological assays use antibodies to detect HSD17B4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HSD17B4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HSD17B4 antibodies...
Designing a Western blot for HSD17B4? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the HSD17B4 Western Blot GuideHSD17B4 Infographic by Boster Bio
All HSD17B4 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IHC, WB
$370
Cat # PA1727
100 μg/vial
Cat # PA1727
100 μg/vial
Human, Mouse, Rat
IHC, WB
$370
Cat # A02923
100 μg/vial
Cat # A02923
100 μg/vial
Anti-Hydroxysteroid (17 beta) Dehydrogenase 4 (HSD17B4) Mouse Monoclonal Antibody [Clone ID: OTI4C4]
Human, Mouse, Rat
IF, IHC, WB
$523
Cat # M02923
100 µl
Cat # M02923
100 µl
Human
$628
Cat # LS003295
20 µg, 100 µg
Cat # LS003295
20 µg, 100 µg
HSD17B4 Overview
Facts about Peroxisomal multifunctional enzyme type 2.
Peroxisomal multifunctional enzyme type 2 (HSD17B4)
Bifunctional enzyme acting on the peroxisomal beta- oxidation pathway for fatty acids. Catalyzes the formation of 3- ketoacyl-CoA intermediates from both straight-chain and 2-methyl- branched-chain fatty acids.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | HSD17B4 |
| Uniprot: | P51659 |
| Entrez: | 3295 |
Family
| Belongs to: |
|---|
| short-chain dehydrogenases/reductases (SDR) family |
Alternative Names
12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase; 7-alpha; D-bifunctional protein; EDH17B4; hydroxysteroid (17-beta) dehydrogenase 4; MPF-2; peroxisomal multifunctional enzyme type 2,17-beta-HSD IV; peroxisomal multifunctional protein 2,17beta-estradiol dehydrogenase type IV; peroxisomal; short chain dehydrogenase/reductase family 8C, member 1,3-alpha
Molecular Weight
Mass (kDA):
79.686 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 5q23.1 |
| Sequence: | 5; NC_000005.10 (119452497..119542332) |
Tissue Specificity
Present in many tissues with highest concentrations in liver, heart, prostate and testis.
Subcellular Localizations
Peroxisome.
Diseases
- Peroxisomal Disorders
- Protein Deficiency
- Malignant Neoplasms
- Zellweger Syndrome
- Adrenoleukodystrophy
- Neoplasms
- Malignant Neoplasm Of Prostate
- Prostatic Neoplasms
- Refsum Disease
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Muscle Hypotonia
Pathways
- Fatty Acid Beta-oxidation
- Conjugation
- Methylation
- Dna Methylation
- Fatty Acid Oxidation
- Transport
- Cell Growth
- Pathogenesis
- Aging
- Brain Development
- Oxidative Phosphorylation
- Dosage Compensation
- Spermatogenesis
PTMs
- Oxidation
- Methylation
- Hydroxylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HSD17B4
bosterbio.com/bosterbio-gene-info-cards/HSD17B4
References
PMID: 7487879 by Adamski J., et al. Molecular cloning of a novel widely expressed human 80 kDa 17 beta- hydroxysteroid dehydrogenase IV.
PMID: 9089413 by Jiang L.L., et al. Structure of D-3-hydroxyacyl-CoA dehydratase/D-3-hydroxyacyl-CoA dehydrogenase bifunctional protein.
1 Publications of Boster HSD17B4 Antibodies & ELISA Kits
- PubMed ID: 30453308, Correlation between HSD17B4 expression in rat liver cancer tissues and inflammat...
*More publications can be found for each product on its corresponding product page