Anti-Interferon gamma/IFNG Antibody
Rabbit IgG polyclonal antibody for Interferon gamma(IFNG) detection. Tested with WB in Human. Cited in 5 publication(s).
Anti-Interferon gamma/IFNG Antibody Info At A Glance
|Product Name||Anti-Interferon gamma/IFNG Antibody
See all IFN-gamma primary antibodies, ELISA kits and proteins
|Storage & Handling||At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.|
|Description||Polyclonal antibody for INTERFERON GAMMA/IFNG detection. Host: Rabbit.Size: 100μg/vial. Tested applications: WB. Reactive species: Human. INTERFERON GAMMA/IFNG information: Molecular Weight: 19348 MW; Subcellular Localization: Secreted; Tissue Specificity: Released primarily from activated T lymphocytes.|
|Cite This Product||Anti-Interferon gamma/IFNG Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # PA1493)|
|Similar Products From
|Anti-Interferon gamma/IFNG Antibody may replace the following items: sc 101424|sc 1377|sc 1379|sc 166800|sc 32813|sc 373727|sc 390800|sc 47700|sc 51973|sc 51974|sc 51975|sc 52555|sc 52556|sc 52681|sc 52682|sc 52811|sc 52862|sc 52863|sc 57208|sc 57209|sc 57210|sc 57211|sc 57212|sc 59995|sc 65286|sc 65352|sc 65418|sc 73303|sc 73392|sc 74108|sc 8308|sc 8423.|
*This antibody is predicted to react with the above species based on antigen sequence similarities. Our Boster Guarantee covers the use of this product with the above species.
*Our Boster Guarantee covers the use of this product in the above tested applications.
*Innovating Scientists reward: if you test this antibody on a species or application not listed above and share with us your results, we will provide you a full credit to purchase Boster products.
|Related Products||Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot.
*Blocking peptide can be purchased at $50. Contact us for more information.
**Boster also offers various secondary antibodies for Immunoflourescecne and IHC. Take advantage of the buy 1 primary antibody get 1 secondary antibody for free promotion all year round.
|Immunogen||A synthetic peptide corresponding to a sequence at the C-terminus of human IFN gamma(151-166aa KRKRSQMLFRGRRASQ).|
|Cross Reactivity||No cross reactivity with other proteins|
Gene/Protein Basic Information For IFNG (Source: Uniprot.org, NCBI)
|NCBI Gene Id||3458|
|Species Of This Entry||Human|
|Protein Name||Interferon gamma|
|Superfamily||type II (or gamma) interferon family|
|Alternative Names||IFN-gamma|IFG; IFI; IFNG; IFNgamma; IFN-gamma; Immune interferon; interferon gamma; interferon, gamma|
|Post Tranlational Modifications||Acetylation; Methylation; Phosphorylation; Demethylation|
|Gene Location||12q15, on Chromasome 12, gene sequence: NC_000012.12 (68154768..68159740, complement)|
*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".
Ontology For IFNG (Source: Uniprot.org, NCBI)
|Protein Function||Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.|
|Tissue Specificity||Released primarily from activated T lymphocytes.|
|Related Diseases||Inflammation; Neoplasms; Infective Disorder; Tuberculosis; Malignant Neoplasms; Autoimmune Reaction; Sclerosis; Dysequilibrium Syndrome; Innate Immune Response; Multiple Sclerosis; Diabetes Mellitus; Virus Diseases; Hepatitis; Asthma; Autoimmune Diseases; Diabetes Mellitus, Insulin-dependent; Inflammatory Response; Cholangiocarcinoma; Tuberculosis, Pulmonary; Leukemia|
|Related Pathways||Immune Response; Pathogenesis; Secretion; Cell Differentiation; Methylation; Cytokine Production; Inflammatory Response; Innate Immune Response; Histone Acetylation; Cell Cycle; Localization; Cell Death; Cell Proliferation; Dna Methylation; Cell Activation; Luteolysis; Macrophage Activation; T Cell Differentiation; Chromatin Remodeling; Cytokine Secretion|
|Background||Interferon-gamma(IFN-gamma) is an inflammatory cytokine that has been implicated in the development of fibrosis in inflamed tissues. The production of IFN-gamma, which is under genetic control, can influence the development of fibrosis in lung allografts. IFN-gamma is also produced by natural killer(NK) cells and most prominently by CD8 cytotoxic T cells, and is vital for the control of microbial pathogens. Interferon gamma is believed to be crucial for host defence against many infections. Genetically determined variability in IFN-gamma and expression might be important for the development of tuberculosis. IFN-gamma activates human macrophage oxidative metabolism and antimicrobial activity. In addition to having antiviral activity, IFN-gamma has important immunoregulatory functions. IFN-gamma plays an important role in the control of neointima proliferation.|
|Scientific References||PMID: 6180322 by Gray P.W., et al. Structure of the human immune interferon gene.|
PMID: 6173769 by Gray P.W., et al. Expression of human immune interferon cDNA in E. coli and monkey cells.
Our Boster Quality Guarantee for Anti-Interferon gamma/IFNG Antibody covers its use in the following applications.Western blot, 0.1-0.5μg/ml, Human
*The recommended dilution ratios/concentrations are for reference only and optimal dilutions/concentrations should be determined by the end user.
All lanes: Anti IFN gamma (PA1493) at 0.5ug/ml
Lane 1: Recombinant Human IFN gamma Protein 10ng
Lane 2: Recombinant Human IFN gamma Protein 5ng
Lane 3: Recombinant Human IFN gamma Protein 2.5ng
Lane 4: Recombinant Human IFN gamma Protein 1.25ng
Predicted bind size: 19KD
Observed bind size: 19KD
Boster provides comprehensive technical information for WB, IHC/IF/ICC, Flow Cytometry sample preparation protocols, assay protocols, troubleshooting tips and assay optimization tips.
- Western Blottting Resource Center
- Immunohistochemistry Resource Center
- Flow Cytometry Technical Resource Center
Other Recommended Resources
Here are featured tools and databases that you might find useful.
Total number of citations: 5
|Yan X, Wang D, Liang F, Fu L, Guo C. Hum Vaccin Immunother. 2014;10(12):3491-8. Doi: 10.4161/Hv.36084. Hpv16L1-Attenuated Shigella Recombinant Vaccine Induced Strong Vaginal And Systemic Immune Responses In Guinea Pig Model.||PubMed ID 25483698|
|Somatostatin Inhibits the Production of Interferon-? by Intestinal Epithelial Cells During Intestinal Ischemia?Reperfusion in Macaques||PubMed ID 24798997|
|Somatostatin Improved B Cells Mature in Macaques during Intestinal Ischemia-Reperfusion||PubMed ID 26222793|
|Protective effect of carnosine after chronic cerebral hypoperfusion possibly through suppressing astrocyte activation||PubMed ID 26885268|
|Women with Recurrent Miscarriage Have Decreased Expression of 25-Hydroxyvitamin D3-1?-Hydroxylase by the Fetal-Maternal Interface||PubMed ID 28902929|
Order Product (PA1493)
Domestically in USA and Canada, ships next business day if available in stock.
Note: sample size takes longer to process, average 5-7 days.
All Boster antibodies and ELISA kits are guaranteed to meet the specifications on the data sheet.See Details
Download troubleshooting handbooks for IHC, Western blot and ELISA for FREE.Download Free PDFs Now
Guaranteed product quality
We promise all of our products perform as described in datasheets.